Establishment of a maximal corticomedullary osmotic gradient during chronic administration
of arginine vasopressin (antidiuretic hormone, ADH) to Brattleboro (diabetes insipidus, DI) …

Inhibition of renal Na+,K+-adenosine triphosphatase is an early biochemical manifestation
of gentamicin treatment in rats. Studies with isolated, perfused rat kidneys in filtering and …

… ME TRIMBLE … ME TRIMBLE … difference noted in maximum urine osmolality at these
two ages appears to be closely related to the length of the medulla. The ratios of medullary:cortical …

… taught me that, when you have a long storyto tell, you must start at the beginning, keep going
until you get to the end, and then stop, and to my late mother, Virginia Farmer Trimble, who …

… Science Foundation, who supported me in a style to which I never quite became accustomed.
… He originally suggested this project and has patiently re-aimed me whenever I went astray. …

… In most experiments, uptake of [3H]adenosine (2,5’,83H, 44 Ci/mmol, Amersham) was initiated
by addition of 15-25 ~1 of membrane suspension to 235-245 ~1 of medium. The reaction …

TRIMBLE, h/TE, AND R. EL BOWMAN. Renal Na+ and K+ trans-port: effects of gl ucose,
palmitate, and a-bromopalmitate. Am. J. Physiol. 225 (5): 10574062. 1973.-Rat kidneys were …

The first detection of nonluminous matter from its gravitational effects occurred in 1844, when
Friedrich Wilhelm Bessel announced that several decades of positional measurements of …

LLC-PK1 cells, an established epithelial cell line derived from pig kidney, were tested as a
model system for assessing the role of calcium in gentamicin-induced nephrotoxicity. Cell …

… More convincing evidence for the existence of mediated palmitate transport by BLMV
comes from counterflow experiments where complications due to binding were ruled out and …