Monofluorinated compounds of which rnonofluoroacetic acid is an example may be very toxic
substances having pharmacological actions of remarkably different character in different …

Halogenated aliphatic hydrocarbons (containing 1 to 4 carbon atoms and 1 or more halogen
atoms) and halogenated ethers are reviewed. The anesthetic aspects of chloroform (67663)…

This study was conducted to determine the pharmacokinetic profile of inhaled styrene in
humans. Four male volunteers were exposed to 80 ppm styrene, and blood styrene …

Halogenation modifies the pharmacological properties and uses of a host of compounds.
This is accomplished at the molecular level by different mechanisms, several of which are …

… occurring in the intact animal has been reviewed by Chenoweth and McCarty. 16 Specific
… Chenoweth et ~1.18 studied the rate of uptake and clearance of the anesthetics from dogs …

The pharmacokinetics and metabolism of 1,4‐dioxane were determined in four healthy male
volunteers exposed to 50 ppm dioxane vapor for 6 hr. Samples of blood and urine collected …

The inhalation toxicity of ethylene oxide cyclic tetramer vapor (EOCT), a synthetic compound,
has been evaluated. Rats were exposed to 0.5 and 1.0 ppm ethylene oxide cyclic tetramer …

Determinations were made of ethanol preference and behavioral tolerance in 4 experiments
with inbred strains of mice. High-and low-preference strains were compared on neural …

The in vitro metabolism of halothane and methoxyflurane has been investigated. With either
chlorine-36 or carbon-14-labeled material, it has been found that the chlorine is …

WE have found that nest-building is ideally suited for the study of the effects of hallucinogenic
drugs. Strains of laboratory mice differ in their nest-building activity. Males of the C57B1/6j …