The actions of the active principle of marihuana, A 9-tetrahydrocannabinol, are mimicked by
synthetic cannabinoid agonists showing high potency and enantioselectivity in behavioral …

Advances in antiretroviral medications have resulted in precipitous declines in HIV-associated
morbidity and mortality; however, high levels of adherence are crucial to the success of …

The product of the ABCB1 gene, P-glycoprotein (PGP), is a transmembrane active efflux
pump for a variety of drugs. It is a putative mechanism of multidrug resistance in a range of …

1.1. Methodology and Evidence Review The recommendations listed in this document are,
whenever possible, evidence based. An extensive evidence review was conducted through …

The determination and characterization of a cannabinoid receptor from brain are reported. A
biologically active bicyclic cannabinoid analgetic CP-55,940 was tntium-Iabeled to high …

[3H]CP 55,940, a radiolabeled synthetic cannabinoid, which is 10-100 times more potent in
vivo than delta 9-tetrahydrocannabinol, was used to characterize and localize a specific …

not override in any way whatsoever the individual responsibility of health professionals to
make appropriate and accurate decisions in consideration of each patient’s health condition …

… One of May’s compounds, (-)-9-nor-9@-hydroxyhexahydrocannabinol (P-HHC), was used as
a lead compound by Johnson and … 1; Johnson and Melvin, 1986) and by potencies in vivo (…

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted through October 2011 and includes selected other …

Several small studies have suggested beneficial effects of long-term β-blocker treatment in
idiopathic dilated cardiomyopathy. Our large multicentre study aimed to find out whether …