Intracellular σ1 receptor modulates phospholipase C and protein kinase C activities in the brainstem

MP Morin-Surun, T Collin… - Proceedings of the …, 1999 - National Acad Sciences
Most physiological effects of σ 1 receptor ligands are sensitive to pertussis toxin, suggesting
a coupling with cell membrane-bound G proteins. However, the cloning of the σ 1 receptor …

Genetic identification of a hindbrain nucleus essential for innate vocalization

…, AJ Murray, MP Morin-Surun… - Proceedings of the …, 2017 - National Acad Sciences
Vocalization in young mice is an innate response to isolation or mechanical stimulation.
Neuronal circuits that control vocalization and breathing overlap and rely on motor neurons that …

Activation of microglia and astrocytes in the nucleus tractus solitarius during ventilatory acclimatization to 10% hypoxia in unanesthetized mice

…, J Champagnat, MP MorinSurun - Journal of …, 2014 - Wiley Online Library
Nucleus tractus solitarius (NTS) is the integrative sensory relay of autonomic functions in the
brainstem. To explore the nonneuronal cellular basis of central chemosensitivity during the …

Prenatal development of central rhythm generation

J Champagnat, MP Morin-Surun, J Bouvier… - Respiratory physiology …, 2011 - Elsevier
Foetal breathing in mice results from prenatal activity of the two coupled hindbrain
oscillators considered to be responsible for respiratory rhythm generation after birth: the pre-Bötzinger …

Progesterone reverses the neuronal responses to hypoxia in rat nucleus tractus solitarius in vitro

O Pascual, MP MorinSurun, B Barna… - The Journal of …, 2002 - Wiley Online Library
The nucleus tractus solitarius (NTS) is a relay nucleus that integrates peripheral chemoreceptor
input in response to hypoxia and hence influences the generation of respiratory rhythm. …

Developmental basis of the rostro-caudal organization of the brainstem respiratory rhythm generator

J Champagnat, MP Morin-Surun… - … of the Royal …, 2009 - royalsocietypublishing.org
The Hox genetic network plays a key role in the anteroposterior patterning of the rhombencephalon
at pre- and early-segmental stages of development of the neural tube. In the mouse, …

Protein kinase C-dependent potentiation of intracellular calcium influx by σ1 receptor agonists in rat hippocampal neurons

FP Monnet, MP Morin-Surun, J Leger… - Journal of Pharmacology …, 2003 - ASPET
Intracellular calcium concentration ([Ca 2+ ] i ) plays a major role in neuronal excitability,
especially that triggered by the N-methyl-d-aspartate (NMDA)-sensitive glutamatergic receptor. …

Pregnenolone sulfate enhances long‐term potentiation in CA1 in rat hippocampus slices through the modulation of N‐methyl‐D‐aspartate receptors

…, M Schumacher, MP MorinSurun - Journal of …, 2004 - Wiley Online Library
Among the different steroids found in the brain, pregnenolone sulfate (3β‐hydroxy‐5‐pregnen‐20‐one‐3‐sulfate;
PREGS) is known to enhance hippocampal‐associated memory. The …

Different effects of μ and δ opiate agonists on respiration

MP Morin-Surun, E Boudinot, G Gacel… - European journal of …, 1984 - Elsevier
… their pharmacological properties have been studied on bulbar respiratory neurons, and were
shown to be related to their stereospecific binding with opiate receptors (Morin-Surun et al., …

Excitatory effects of iontophoretically applied substance P on neurons in the nucleus tractus solitarius of the cat: lack of interaction with opiates and opioids

MP Morin-Surun, D Jordan, J Champagnat, KM Spyer… - Brain research, 1984 - Elsevier
The effects of iontophoretically applied substance P (SP), (d-Pro 2 ,d-Trp 7,9 )-SP and (d-Pro
4 ,d-Trp 7,9,10 )-SP were studied on neurons identified by their histological location in the …