User profiles for M Michaelides

Michel Michaelides

- Verified email at ucl.ac.uk - Cited by 21227

Mike Michaelides

- Verified email at nih.gov - Cited by 4907

The neuroscience of drug reward and addiction

ND Volkow, M Michaelides, R Baler - Physiological reviews, 2019 - journals.physiology.org
M. Michaelides is a cofounder and owns stock in Metis Laboratories, Inc. No conflicts of …
Ahmad FB, Escobedo LA, Rossen LM, Spencer MR, Warner M, Provisional Drug Overdose …

Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options

…, RW Strauss, K Fujinami, M Michaelides - British Journal of …, 2017 - bjo.bmj.com
Stargardt disease (STGD1; MIM 248200) is the most prevalent inherited macular dystrophy
and is associated with disease-causing sequence variants in the gene ABCA4. Significant …

The cone dysfunction syndromes

M Michaelides, DM Hunt, AT Moore - British Journal of Ophthalmology, 2004 - bjo.bmj.com
… L and M visual pigment genes is controlled by an upstream locus control region (LCR).
Mutations in the L and M pigment gene array that result in the lack of functional L and M pigments…

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

…, RF Dannals, MG Pomper, A Bonci, M Michaelides - Science, 2017 - science.org
… (M) Efflux (E) ratios of CNO and clozapine in the P-gp assay, two… Liu, and M. Morales for
research and administrative support … Liu, and M. Morales for research and administrative support …

[HTML][HTML] Long-term effect of gene therapy on Leber's congenital amaurosis

…, SM Petersen-Jones, M Michaelides… - … England Journal of …, 2015 - Mass Medical Soc
Background Mutations in RPE65 cause Leber’s congenital amaurosis, a progressive retinal
degenerative disease that severely impairs sight in children. Gene therapy can result in …

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

…, C Sun, PA Cole, SH Rosenberg, MR Michaelides… - Nature, 2017 - nature.com
The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases (HATs)
and histone deacetylases (HDACs), is a major epigenetic regulatory mechanism of …

A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study): 12-month data: report 2

M Michaelides, A Kaines, RD Hamilton, S Fraser-Bell… - Ophthalmology, 2010 - Elsevier
PURPOSE: To report the findings at 1 year of a study comparing repeated intravitreal
bevacizumab (ivB) and modified Early Treatment of Diabetic Retinopathy Study (ETDRS) macular …

A comparison of the causes of blindness certifications in England and Wales in working age adults (16–64 years), 1999–2000 with 2009–2010

G Liew, M Michaelides, C Bunce - BMJ open, 2014 - bmjopen.bmj.com
Objectives To report on the causes of blindness certifications in England and Wales in working
age adults (16–64 years) in 2009–2010; and to compare these with figures from 1999 to …

[PDF][PDF] Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease

…, E Wakeling, WH Ouwehand, M Michaelides… - The American Journal of …, 2017 - cell.com
Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 individuals …

Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

…, Y Shaham, CA Zarate Jr, M Michaelides - Molecular …, 2021 - nature.com
… beam crossing and traveled distance were converted to m and binned into 5 min time bins.
… (on expression day) as infrared beam crossing and traveled distance were converted to m. …