Toll-like receptors on regulatory T cells: expanding immune regulation
Regulatory T (Treg) cells maintain peripheral tolerance and limit effector responses to prevent
excessive immune-mediated tissue damage. However, recent research reveals that Treg …
excessive immune-mediated tissue damage. However, recent research reveals that Treg …
Difference gel electrophoresis. A single gel method for detecting changes in protein extracts
We describe a modification of two‐dimensional (2‐D) polyacrylamide gel electrophoresis that
requires only a single gel to reproducibly detect differences between two protein samples. …
requires only a single gel to reproducibly detect differences between two protein samples. …
Expression of FOXP3 mRNA is not confined to CD4+ CD25+ T regulatory cells in humans
ME Morgan, JHM van Bilsen, AM Bakker… - Human immunology, 2005 - Elsevier
Expression of the transcription factor Foxp3 (forkhead box P3) has been implicated as a key
element for CD25 + T regulatory cell function in mice. However, literature over similar …
element for CD25 + T regulatory cell function in mice. However, literature over similar …
Faunal and environmental change in the late Miocene Siwaliks of northern Pakistan
JC Barry, ME Morgan, LJ Flynn, D Pilbeam… - Paleobiology, 2002 - cambridge.org
The Siwalik formations of northern Pakistan consist of deposits of ancient rivers that existed
throughout the early Miocene through the late Pliocene. The formations are highly …
throughout the early Miocene through the late Pliocene. The formations are highly …
Effective treatment of collagen‐induced arthritis by adoptive transfer of CD25+ regulatory T cells
ME Morgan, R Flierman… - Arthritis & …, 2005 - Wiley Online Library
… Morgan and Flierman contributed equally to this work. … Morgan and Flierman
contributed equally to this work. … Morgan and Flierman contributed equally to this work. …
contributed equally to this work. … Morgan and Flierman contributed equally to this work. …
CD25+ cell depletion hastens the onset of severe disease in collagen‐induced arthritis
ME Morgan, RPM Sutmuller, HJ Witteveen… - Arthritis & …, 2003 - Wiley Online Library
Objective CD4+,CD25+ T regulatory cells may offer opportunities to intervene in the course
of autoimmune disease. We wished to evaluate their potential for influencing systemic and …
of autoimmune disease. We wished to evaluate their potential for influencing systemic and …
Carbon isotopic evidence for the emergence of C4 plants in the Neogene from Pakistan and Kenya
ME Morgan, JD Kingston, BD Marino - Nature, 1994 - nature.com
DETAILED palaeorecords of terrestrial environments are critical for interpretations of the
late Miocene mammalian evolution. Here we assess the development of modern tropical …
late Miocene mammalian evolution. Here we assess the development of modern tropical …
A 16-Ma record of paleodiet using carbon and oxygen isotopes in fossil teeth from Pakistan
J Quade, TE Cerlinga, JC Barry, ME Morgan… - Chemical Geology …, 1992 - Elsevier
The Siwalik Sequence of northern Pakistan contains a 16-Ma record of paleosol carbonate
and fossil teeth from which a record of paleovegetation can potentially be reconstructed and …
and fossil teeth from which a record of paleovegetation can potentially be reconstructed and …
Ecological changes in Miocene mammalian record show impact of prolonged climatic forcing
C Badgley, JC Barry, ME Morgan… - Proceedings of the …, 2008 - National Acad Sciences
Geohistorical records reveal the long-term impacts of climate change on ecosystem structure.
A 5-myr record of mammalian faunas from floodplain ecosystems of South Asia shows …
A 5-myr record of mammalian faunas from floodplain ecosystems of South Asia shows …
Lorcaserin (APD356), a Selective 5‐HT2C Agonist, Reduces Body Weight in Obese Men and Women
SR Smith, WA Prosser, DJ Donahue, ME Morgan… - …, 2009 - Wiley Online Library
Lorcaserin (APD356) is a potent, selective 5‐HT 2C agonist with ∼15‐fold and 100‐fold
selectivity vs. 5‐HT 2A and 5‐HT 2B receptors, respectively. This study evaluated the safety and …
selectivity vs. 5‐HT 2A and 5‐HT 2B receptors, respectively. This study evaluated the safety and …