The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
ME Hess, S Hess, KD Meyer, LAW Verhagen… - Nature …, 2013 - nature.com
Dopaminergic (DA) signaling governs the control of complex behaviors, and its deregulation
has been implicated in a wide range of diseases. Here we demonstrate that inactivation of …
has been implicated in a wide range of diseases. Here we demonstrate that inactivation of …
[HTML][HTML] A link between FTO, ghrelin, and impaired brain food-cue responsivity
…, K Chandarana, S Manning, ME Hess… - The Journal of …, 2013 - Am Soc Clin Investig
Polymorphisms in the fat mass and obesity-associated gene (FTO) are associated with human
obesity and obesity-prone behaviors, including increased food intake and a preference …
obesity and obesity-prone behaviors, including increased food intake and a preference …
[PDF][PDF] N6-methyladenosine guides mRNA alternative translation during integrated stress response
…, XE Shu, Y Mao, XM Liu, X Yuan, X Zhang, ME Hess… - Molecular cell, 2018 - cell.com
The integrated stress response (ISR) facilitates cellular adaptation to stress conditions via
the common target eIF2α. During ISR, the selective translation of stress-related mRNAs often …
the common target eIF2α. During ISR, the selective translation of stress-related mRNAs often …
[PDF][PDF] AgRP neurons control systemic insulin sensitivity via myostatin expression in brown adipose tissue
…, H Backes, LE Ruud, K Timper, ME Hess… - Cell, 2016 - cell.com
Activation of Agouti-related peptide (AgRP) neurons potently promotes feeding, and chronically
altering their activity also affects peripheral glucose homeostasis. We demonstrate that …
altering their activity also affects peripheral glucose homeostasis. We demonstrate that …
[PDF][PDF] Food perception primes hepatic ER homeostasis via melanocortin-dependent control of mTOR activation
…, DA Morgan, P Gabel, HG Sprenger, ME Hess… - Cell, 2018 - cell.com
Adaptation of liver to the postprandial state requires coordinated regulation of protein synthesis
and folding aligned with changes in lipid metabolism. Here we demonstrate that sensory …
and folding aligned with changes in lipid metabolism. Here we demonstrate that sensory …
An obesity-predisposing variant of the FTO gene regulates D2R-dependent reward learning
…, AB Kühn, J Mauer, L Schilbach, ME Hess… - Journal of …, 2015 - Soc Neuroscience
Variations in the fat mass and obesity-associated (FTO) gene are linked to obesity. However,
the underlying neurobiological mechanisms by which these genetic variants influence …
the underlying neurobiological mechanisms by which these genetic variants influence …
[HTML][HTML] The fat mass and obesity-associated (FTO) gene: obesity and beyond?
ME Hess, JC Brüning - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Genome wide association studies undoubtedly linked variants of the fat mass and obesity-associated
protein (FTO) to obesity. To date, however, knowledge on the mechanisms …
protein (FTO) to obesity. To date, however, knowledge on the mechanisms …
[BOOK][B] Engaging technology in theological education: All that we can't leave behind
ME Hess - 2005 - books.google.com
… me in this quest. His full partnership in maintaining a home and raising our children has freed
me … Alex, though only twelve as of this writing, has already gone far beyond me in his work …
me … Alex, though only twelve as of this writing, has already gone far beyond me in his work …
[HTML][HTML] Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling
…, W Reichardt, N Baeuerle, ME Hess… - Nature …, 2020 - nature.com
Cathepsin D (CTSD) is a lysosomal protease and a marker of poor prognosis in breast cancer.
However, the cells responsible for this association and the function of CTSD in cancer are …
However, the cells responsible for this association and the function of CTSD in cancer are …
Democratic spaces: How teachers establish and sustain democracy and education in their classrooms
… Hess is an assistant professor in educational studies in The Patton College of Education at
… So, to me standardized testing is the biggest obstacle because it is important whether we …
… So, to me standardized testing is the biggest obstacle because it is important whether we …