User profiles for Luiz Antonio S Romeiro

Luiz Romeiro

Universidade de Brasília
Verified email at unb.br
Cited by 859

Revisiting the pharmacodynamic uroselectivity of α1-adrenergic receptor antagonists

…, ACS da Silva, AS Pupo, LAS Romeiro… - … of Pharmacology and …, 2019 - ASPET
α 1 -Adrenoceptor (AR) antagonists are widely used for the relief of urinary retention
secondary to benign prostatic hyperplasia (BPH). While the five Food and Drug Administration–…

New multi-target antagonists of α1A-, α1D-adrenoceptors and 5-HT1A receptors reduce human hyperplastic prostate cell growth and the increase of intraurethral …

…, F Chagas-Silva, PAR Souza, LAS Romeiro… - … of Pharmacology and …, 2016 - ASPET
Benign prostatic hyperplasia (BPH) is characterized by stromal cell proliferation and contraction
of the periurethral smooth muscle, causing lower urinary tract symptoms. Current BPH …

[HTML][HTML] The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D4 receptor binding and toxicological assessment

…, KB Reis, R Menegatti, LM Lião, LAS Romeiro… - Biomedicine & …, 2018 - Elsevier
Piperazine is a promising scaffold for drug development due to its broad spectrum of biological
activities. Based on this, the new piperazine-containing compound LQFM018 (2) [ethyl 4-(…

Pharmacological characterization of N1-(2-methoxyphenyl)-N4-hexylpiperazine as a multi-target antagonist of α1A1D-adrenoceptors and 5-HT1A receptors that …

…, JB Nascimento-Viana, LAS Romeiro… - Naunyn-Schmiedeberg's …, 2014 - Springer
Benign prostatic hyperplasia (BPH) is a progressive disease related to the imbalance of cell
growth and apoptosis, and it plays a key role in the development of lower urinary tract …

[HTML][HTML] Novas estratégias terapêuticas para o tratamento da depressão: uma visão da química medicinal

LAS Romeiro, CAM Fraga, EJ Barreiro - Química Nova, 2003 - SciELO Brasil
Luiz Antonio Soares RomeiroLuiz Antonio Soares Romeiro I ; Carlos Alberto Manssour
Fraga II ; Eliezer J. … Universidade Católica de Brasília a concessão da bolsa PIC à LAS Romeiro. …

Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease

…, O Soukup, J Korábečný, NC Romeiro… - European Journal of …, 2016 - Elsevier
Romeiro j , Newton G. Castro c , Maria Laura Bolognesi d , Luiz Antonio Soares Romeiro
a b … A 300 s time scan of fluorescence intensity was carried out (λ exc …

The α1-adrenoceptor-mediated human hyperplastic prostate cells proliferation is impaired by EGF receptor inhibition

…, LAC Branco, PR Feijó, LAS Romeiro… - Life sciences, 2019 - Elsevier
… Feijó a , Luiz Antonio Soares Romeiro d , Luiz Eurico Nasciutti c , François Noël a , J. Adolfo
… 5 nM) were pre-incubated for 100 s before addition of the agonists, and their concentrations …

[HTML][HTML] Molecular evaluation of anti-inflammatory activity of phenolic lipid extracted from cashew nut shell liquid (CNSL)

…, GS Heyn, PS Alves, LAS Romeiro… - … and alternative medicine, 2018 - Springer
Background Anacardium occidentale L phenolic lipid (LDT11) is used in traditional medicine
as anti-inflammatory, astringent, antidiarrheal, anti-asthmatic and depurative. Phenolic …

[HTML][HTML] Cashew nut shell liquid (CNSL) as a source of drugs for Alzheimer's disease

…, L de Camargo Nascente, LAS Romeiro… - Molecules, 2021 - mdpi.com
Alzheimer’s disease (AD) is a complex neurodegenerative disorder with a multifaceted
pathogenesis. This fact has long halted the development of effective anti-AD drugs. Recently, a …

Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties

…, J Korábečný, ML Bolognesi, LAS Romeiro - RSC Medicinal …, 2021 - pubs.rsc.org
As part of our efforts to develop sustainable drugs for Alzheimer's disease (AD), we have
been focusing on the inexpensive and largely available cashew nut shell liquid (CNSL) as a …