Human immunoglobulin E flexes between acutely bent and extended conformations
…, A Oxbrow, J Delgado, LK Shuttleworth… - Nature structural & …, 2014 - nature.com
Crystallographic and solution studies have shown that IgE molecules are acutely bent in
their Fc region. Crystal structures reveal the Cɛ2 domain pair folded back onto the Cɛ3-Cɛ4 …
their Fc region. Crystal structures reveal the Cɛ2 domain pair folded back onto the Cɛ3-Cɛ4 …
Seletalisib: characterization of a novel, potent, and selective inhibitor of PI3Kδ
…, MJ Powell, J Delgado, LK Shuttleworth… - … of Pharmacology and …, 2017 - ASPET
Phosphoinositide 3-kinases (PI3K) are key signaling enzymes regulating cellular survival,
development, and function. Expression of the PI3Kδ isoform is largely restricted to leukocytes …
development, and function. Expression of the PI3Kδ isoform is largely restricted to leukocytes …
Sorption of Heavy Metals to the Filamentous Bacterium Thiothrix Strain A1
KL Shuttleworth, RF Unz - Applied and environmental …, 1993 - Am Soc Microbiol
… Shuttleworth and Unz (26) determined that copper was more toxic than either nickel or zinc
to Thiothrix strain Al, and results from the present study revealed that Thiothrix strain Al had …
to Thiothrix strain Al, and results from the present study revealed that Thiothrix strain Al had …
Influence of metals and metal speciation on the growth of filamentous bacteria
KL Shuttleworth, RF Unz - Water research, 1991 - Elsevier
Calcium, copper, nickel and zinc were examined for their effect on the growth of axenic
filamentous bacteria which included strains of Thiothrix, type 021N and type 1701. All organisms …
filamentous bacteria which included strains of Thiothrix, type 021N and type 1701. All organisms …
[BOOK][B] Toxicity and sorption of heavy metals to filamentous bacteria
KL Shuttleworth - 1991 - search.proquest.com
… of heavy metals to filamentous bacteria Shuttleworth, Kay L., Ph.D. … E H e : k e r te E o r J
e r- 1. rh s te r- t i «) … X 1.0) samples were diluted with distilled water to an OD of K. 1,0 before …
e r- 1. rh s te r- t i «) … X 1.0) samples were diluted with distilled water to an OD of K. 1,0 before …
[HTML][HTML] Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells
…, MR Girotti, G Sibbet, EB Higgs, MK Shuttleworth… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent data implicate elevated transforming growth factor-β (TGFβ) signalling in BRAF inhibitor
drug-resistance mechanisms, but the potential for targeting TGFβ signalling in cases of …
drug-resistance mechanisms, but the potential for targeting TGFβ signalling in cases of …
Envisioning the future with 'compassionate conservation': An ominous projection for native wildlife and biodiversity
…, C Shuttleworth, CT Tamessar, WA Taylor, K Tuft… - Biological …, 2020 - Elsevier
The ‘Compassionate Conservation’ movement is gaining momentum through its promotion
of ‘ethical’ conservation practices based on self-proclaimed principles of ‘first-do-no-harm’ …
of ‘ethical’ conservation practices based on self-proclaimed principles of ‘first-do-no-harm’ …
Overview of the large-scale biosphere–atmosphere experiment in Amazonia Data Model Intercomparison Project (LBA-DMIP)
…, K Schaefer, M Shi, WJ Shuttleworth… - Agricultural and Forest …, 2013 - Elsevier
A fundamental question connecting terrestrial ecology and global climate change is the
sensitivity of key terrestrial biomes to climatic variability and change. The Amazon region is such …
sensitivity of key terrestrial biomes to climatic variability and change. The Amazon region is such …
[PDF][PDF] Mutational activation of BRAF confers sensitivity to TGFβ inhibitors in human cancer cells
…, MR Girotti, G Sibbet, EB Higgs, MK Shuttleworth… - scholarlypublications …
Recent data implicate elevated transforming growth factor-β (TGFβ) signaling in BRAF inhibitor
drug-resistance mechanisms, but the potential for targeting TGFβ signaling in cases of …
drug-resistance mechanisms, but the potential for targeting TGFβ signaling in cases of …
[HTML][HTML] Restoration of blanket peat moorland delays stormflow from hillslopes and reduces peak discharge
EL Shuttleworth, MG Evans, M Pilkington… - Journal of Hydrology …, 2019 - Elsevier
Over the past 15 years there has been a proliferation of projects aiming to restore the structure
and function of UK upland blanket mires, primarily by revegetation of bare peat and the …
and function of UK upland blanket mires, primarily by revegetation of bare peat and the …