The molecular diversity of voltage-activated calcium channels was established by studies
showing that channels could be distinguished by their voltage-dependence, deactivation and …

Low voltage-activated (T-type) calcium currents are observed in many central and
peripheral neurons and display distinct physiological and functional properties. Using in situ …

Voltage-activated Ca 2+ channels exist as multigene families that share common structural
features. Different Ca 2+ channels are distinguished by their electrophysiology and …

Nickel has been proposed to be a selective blocker of low-voltage-activated, T-type calcium
channels. However, studies on cloned high-voltage-activated Ca 2+ channels indicated that …

Low voltage-activated Ca 2+ channels play important roles in pacing neuronal firing and
producing network oscillations, such as those that occur during sleep and epilepsy. Here we …

The cardiac sodium channel α subunit (RHI) is less sensitive to tetrodotoxin (TTX) and
saxitoxin (STX) and more sensitive to cadmium than brain and skeletal muscle (μl) isoforms. An …

Calcium ion (Ca 2+ ) influx through voltage-gated Ca 2+ channels is important for the
regulation of vascular tone. Activation of L-type Ca 2+ channels initiates muscle contraction; …

Mibefradil is a tetralol derivative chemically distinct from other calcium channel antagonists.
It is a very effective antihypertensive agent that is thought to achieve its action via a higher …

Pressor effects of the vasoconstrictor hormone arginine vasopressin (AVP), observed when
systemic AVP concentrations are less than 100 pM, are important for the physiological …

Expression of rat α1G, human α1H and rat α1I subunits of voltage‐activated Ca 2 + channels
in HEK‐293 cells yields robust Ca 2 + inward currents with 1.25 mm Ca 2 + as the charge …