Fenamates: a novel class of reversible gap junction blockers
…, ADG de Roos, PHJ Peters, LH de Haan… - … of Pharmacology and …, 2001 - ASPET
The effect of fenamates on gap junctional intercellular communication was investigated in
monolayers of normal rat kidney (NRK) fibroblasts and of SKHep1 cells overexpressing the …
monolayers of normal rat kidney (NRK) fibroblasts and of SKHep1 cells overexpressing the …
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
…, HJ Grabe, KH Greiser, PJF Groenen, HG de Haan… - Nature …, 2016 - nature.com
The genetic architecture of human reproductive behavior—age at first birth (AFB) and number
of children ever born (NEB)—has a strong relationship with fitness, human development, …
of children ever born (NEB)—has a strong relationship with fitness, human development, …
[HTML][HTML] Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells
S Bhattacharjee, LHJ de Haan, NM Evers… - Particle and fibre …, 2010 - Springer
Background Surface charge and oxidative stress are often hypothesized to be important factors
in cytotoxicity of nanoparticles. However, the role of these factors is not well understood. …
in cytotoxicity of nanoparticles. However, the role of these factors is not well understood. …
Species-specific antagonism of Ah receptor action by 2, 2′, 5, 5′-tetrachloro-and 2, 2′, 3, 3′, 4, 4′-hexachlorobiphenyl
…, PM Garrison, K Tullis, LHJ de Haan… - European Journal of …, 1995 - Elsevier
Using recombinant cell lines showing Ah receptor-controlled expression of a luciferase
reporter gene, the interaction of di-ortho-substituted polychlorinated biphenyls (PCBs) with Ah …
reporter gene, the interaction of di-ortho-substituted polychlorinated biphenyls (PCBs) with Ah …
Directional dominance on stature and cognition in diverse human populations
Homozygosity has long been associated with rare, often devastating, Mendelian disorders 1,
and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness 2. …
and Darwin was one of the first to recognize that inbreeding reduces evolutionary fitness 2. …
[PDF][PDF] Germline variants in tumor suppressor FBXW7 lead to impaired ubiquitination and a neurodevelopmental syndrome
…, M Wallis, S Jansen, Q Waisfisz, H de Haan… - The American Journal of …, 2022 - cell.com
Neurodevelopmental disorders are highly heterogenous conditions resulting from abnormalities
of brain architecture and/or function. FBXW7 (F-box and WD-repeat-domain-containing 7…
of brain architecture and/or function. FBXW7 (F-box and WD-repeat-domain-containing 7…
The pro-oxidant chemistry of the natural antioxidants vitamin C, vitamin E, carotenoids and flavonoids
IMCM Rietjens, MG Boersma, L de Haan… - Environmental …, 2002 - Elsevier
Natural antioxidants like vitamin C, vitamin E, carotenoids, and polyphenols like flavonoids,
are at present generally considered to be beneficial components from fruit and vegetables. …
are at present generally considered to be beneficial components from fruit and vegetables. …
Synthesis and cytotoxicity of silicon nanoparticles with covalently attached organic monolayers
A series of highly monodisperse silicon nanoparticles (Si NPs) with either positively (amine),
neutral (azide) or negatively (carboxylic acid) charged covalently attached organic …
neutral (azide) or negatively (carboxylic acid) charged covalently attached organic …
The regulatory framework across international jurisdictions for risks associated with consumption of botanical food supplements
…, KO Wong, ALL Yap, LHJ De Haan… - … Reviews in Food …, 2017 - Wiley Online Library
Dietary supplements, including those containing botanical ingredients and botanical‐derived
compounds, have been marketed to consumers globally for many decades. However, the …
compounds, have been marketed to consumers globally for many decades. However, the …
[PDF][PDF] Lenny Kamelia, Jochem Louisse, Laura de Haan, Anna Maslowska-Gornicz, Hans B.
AB Ketelslegers, IMCM Rietjens, PJ Boogaard - The role of polycyclic … - edepot.wur.nl
… The cells were incubated overnight (24 h) at 37oC/5% CO2 and then exposed for 6 h to the
test compounds in triplicate. Six hours was chosen, over 24 h, for the exposure time for the …
test compounds in triplicate. Six hours was chosen, over 24 h, for the exposure time for the …