Human neuronal nicotinic acetylcholine receptors (nAChRs) hα2β2, hα2β4, hα3β2, hα3β4,
hα4β2, hα4β4 and hα7 were expressed in Xenopus oocytes and tested for their sensitivities …

… direct adenylate cyclase activator forskolin (Chavez-Noriega … adenylate cyclase inhibitors
(Chavez-Noriega and Stevens, … on the field EPSP (ChavezNoriega ard Stevens, 1992a). Only …

Expression of functional, recombinant α7 nicotinic acetylcholine receptors in several
mammalian cell types, including HEK293 cells, has been problematic. We have isolated the …

Alcohol and tobacco use is highly correlated in humans, and studies with animal models
suggest an interaction of alcohol with neuronal nicotinic acetylcholine receptors (nAChRs). The …

In the present study, we describe the characterization of a positive allosteric modulator at
metabotropic glutamate subtype 2 receptors (mGluR2). N-(4-(2-Methoxyphenoxy)-phenyl-N-(2,…

Unlabelled Background The neuronal mechanisms responsible for dissociative anesthesia
remain controversial. N-methyl-D-aspartate (NMDA) receptors are inhibited by ketamine and …

Activation of cAMP-dependent protein kinase (kinase A) has recently been shown to enhance
responses evoked by stimulation of α-amino-3-hydroxy-5-methyl-4-isoxazole proprionate (…

Schizophrenia is a debilitating chronic psychiatric illness affecting 1% of the population. The
cardinal features of schizophrenia are positive symptoms (thought disorder, hallucinations, …

cDNA clones encoding human neuronal nicotinic acetylcholine receptor α2, α3, α4, α5, α6,
α7, β2, β3, and β4 subunits were isolated from brainstem, hippocampus, prefrontal cortex, …

Alcohol is known to modulate the activity of a variety of neuroreceptors and ion channels.
Recently, neuronal nicotinic acetylcholine receptors (nnAChRs) have become a specific focus …