[HTML][HTML] Intense exercise promotes adult hippocampal neurogenesis but not spatial discrimination

JH So, C Huang, M Ge, G Cai, L Zhang… - Frontiers in cellular …, 2017 - frontiersin.org
Hippocampal neurogenesis persists throughout adult life and plays an important role in
learning and memory. Although the influence of physical exercise on neurogenesis has been …

Dihydroartemisinin inhibits the growth of pancreatic cells by inducing ferroptosis and activating antitumor immunity

H Zhang, Y Zhuo, D Li, L Zhang, Q Gao, L Yang… - European journal of …, 2022 - Elsevier
Dihydroartemisinin (DHA) exhibits a direct antitumor effect in various tumor models. However,
the mechanism of DHA inducing ferroptosis and activating antitumor immunity remains …

Syringaresinol Resisted Sepsis-Induced Acute Lung Injury by Suppressing Pyroptosis Via the Oestrogen Receptor-β Signalling Pathway

Y Zhuo, L Yang, D Li, L Zhang, Q Zhang, S Zhang, C Li… - Inflammation, 2022 - Springer
… Dihua Li analysed and interpreted the data, Lanqiu Zhang wrote the manuscript. Qi Zhang,
Shukun Zhang, Caixia Li, Lihua Cui and Jian Hao participated in the experimental operation. …

Pancreatic stellate cells promote tumor progression by promoting an immunosuppressive microenvironment in murine models of pancreatic cancer

…, Y Zhuo, L Zhang, X Wang, Q Zhang, S Zhang - Pancreas, 2020 - journals.lww.com
Objectives Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of
cancer with poor prognosis. Pancreatic stellate cells (PSCs) play a vital role in PDAC …

Protective role of liriodendrin in mice with dextran sulphate sodium-induced ulcerative colitis

Z Zhang, L Yang, B Wang, L Zhang, Q Zhang… - International …, 2017 - Elsevier
Sargentodoxa cuneata, containing syringaresinol and its glycoside liriodendrin as the main
bioactive compounds, is a well-known traditional Chinese medicine for treating intestinal …

[HTML][HTML] Osthole inhibits pancreatic cancer progression by directly exerting negative effects on cancer cells and attenuating tumor-infiltrating M2 macrophages

…, Z Zhang, C Qiu, L Yang, L Zhang, Q Zhang… - Journal of …, 2018 - Elsevier
Pancreatic cancer has remained a major cause of cancer-related deaths. A hallmark of
pancreatic cancer is extensive stromal reactions, resulting in a unique tumor microenvironment, …

Hydroxytyrosol inhibits LPS-induced neuroinflammatory responses via suppression of TLR-4-mediated NF-κB P65 activation and ERK signaling pathway

L Zhang, J Zhang, X Jiang, L Yang, Q Zhang, B Wang… - Neuroscience, 2020 - Elsevier
Neuroinflammation has been implicated in the mechanism underlying the progression of
neurodegeneration and infectious neuropathology. Growing evidence suggest that …

[HTML][HTML] miR-3065-3p promotes stemness and metastasis by targeting CRLF1 in colorectal cancer

Y Li, J Xun, B Wang, Y Ma, L Zhang, L Yang… - Journal of Translational …, 2021 - Springer
Background Colorectal cancer is one of the most common malignancy in the world. It has
been reported that cancer stem cells (CSCs) serve as the primary drivers of tumorigenesis and …

(−)-Syringaresinol suppressed LPS-induced microglia activation via downregulation of NF-κB p65 signaling and interaction with ERβ

L Zhang, X Jiang, J Zhang, H Gao, L Yang, D Li… - International …, 2021 - Elsevier
Albiziae Cortex (AC) is a well-known traditional Chinese medicine with sedative-hypnotic
effects and neuroprotective ability. However, the bioactive components of AC responsible for …

[HTML][HTML] Optimization of the process for purifying icariin from Herba Epimedii by macroporous resin and the regulatory role of icariin in the tumor immune …

X Zheng, D Li, J Li, B Wang, L Zhang, X Yuan… - Biomedicine & …, 2019 - Elsevier
Pancreatic cancer is a digestive tract malignancy that poses a serious threat to human health.
Compounds derived from traditional Chinese medicines have been an important source of …