… Glycine, L-leucine, or L-phenylalanine was introduced at the terminal amino group of the
new secocompound. On cyclization, the modified seco-compounds yielded the phallo- …

… enzymes, which are selective for the d/l chirality of the substrate. Enzymes producing d(+)-…
related with LDHs producing l(-)-lactate (l(-)-LDHs) [2]. l(-)-LDHs belong to the l-specific NAD-…

… 5 Fiume L: Inhibition of aerobic glycolysis in Yoshida ascites hepatoma by tartronic acid.
Nature 1960; 187: 792–793. 6 Papacostantinou J, Colowick SP: The role of glycolysis in the …

… The crystal structure of human muscle L-lactate dehydrogenase M chain complexed with
oxamic acid and NADH (PDB ID: 1I10)30 was downloaded from the PDB (http://www.rcsb.org). …

Galloflavin (GF), a recently identified lactate dehydrogenase inhibitor, hinders the
proliferation of cancer cells by blocking glycolysis and ATP production. The aim of the present …

The expression of the asialoglycoprotein receptor (ASGP-R) on human hepatocellular
carcinoma (HCC) cells might be exploited to reduce the extrahepatic toxicity of DNA synthesis …

… Fiume et al., submitted for publication). On the other hand, the synthesis of L-HSA–DOXO has
a drawback, since the thiolation of L… EMCH to L-HSA. We made available the HS-groups of …

1. Injection of α-amanitin to mice causes a decreased incorporation of [6− 14 C]-orotic acid
into liver RNA in vivo. 2. The activity of RNA polymerase activated by Mn 2+ and ammonium …

… FIUME, M. LA PLACA, ANNA MANNINI-PALENZONA, F. NOVELLO, AND F. … D., BA
Jant, L. Sokoloff, and S. Kaufman. … Stirpe, F., and L. Fiumne. Studies on the pathogenesis …

… Peritoneal dialysis (2 L exchanged per hour) and forced diuresis (urinary output higher than
… Group l included patients with absent to mild liver damage, an uneventful clinical course, …