User profiles for L O'Connor

Laura Keyes (O'Connor)

Senior Regulatory Practice and Research Manager, HIQA
Verified email at hiqa.ie
Cited by 2860

[HTML][HTML] Bim: a novel member of the Bcl‐2 family that promotes apoptosis

L O'Connor, A Strasser, LA O'Reilly… - The EMBO …, 1998 - embopress.org
… When we also introduced the bim L vector into L929 cells stably expressing human Bcl‐2,
the similarity of the anti‐EE staining pattern of these cells (Figure 3C) to that of those …

The Religious Commitment Inventory--10: Development, refinement, and validation of a brief scale for research and counseling.

…, JT Berry, KH Bursley, L O'Connor - Journal of counseling …, 2003 - psycnet.apa.org
The authors report the development of the Religious Commitment Inventory--10 (RCI-10),
used in 6 studies. Sample sizes were 155, 132, and 150 college students; 240 Christian church…

[HTML][HTML] Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection

…, K Jones, J Dunne, A Mooney, F Gaffney, L O'Connor… - PloS one, 2020 - journals.plos.org
Fatigue is a common symptom in those presenting with symptomatic COVID-19 infection.
However, it is unknown if COVID-19 results in persistent fatigue in those recovered from acute …

Apoptosis signaling

A Strasser, L O'Connor, VM Dixit - Annual review of biochemistry, 2000 - annualreviews.org
… Bcl-2 and Bcl-x L have been shown to be regulated by phosphorylation (152, 153, 154),
and … We have also been puzzled by the observation that there are mutants of Bcl-x L that are …

Large‐scale mapping of human protein–protein interactions by mass spectrometry

…, MD Robinson, L O'Connor… - Molecular systems …, 2007 - embopress.org
Mapping protein–protein interactions is an invaluable tool for understanding protein function.
Here, we report the first large‐scale study of protein–protein interactions in human cells …

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

VS Marsden, L O'Connor, LA O'Reilly, J Silke, D Metcalf… - Nature, 2002 - nature.com
Apoptosis is an evolutionarily conserved cell suicide process executed by cysteine proteases
(caspases) and regulated by the opposing factions of the Bcl-2 protein family 1 , 2 . …

Consumption of sugar sweetened beverages, artificially sweetened beverages, and fruit juice and incidence of type 2 diabetes: systematic review, meta-analysis, and …

F Imamura, L O'Connor, Z Ye, J Mursu, Y Hayashino… - Bmj, 2015 - bmj.com
… Fumiaki Imamura,1 Laura OConnor,1 Zheng Ye,1 Jaakko Mursu,2 Yasuaki Hayashino,3,
4 Shilpa N Bhupathiraju,5 Nita G Forouhi1 … n a l co … l re s id u a lc o n fo u n d in g . S …

Forgivingness, vengeful rumination, and affective traits

…, LE O'Connor, L Parrott III… - Journal of …, 2005 - Wiley Online Library
Trait forgivingness is the disposition to forgive interpersonal transgressions over time and
across situations. We define forgiveness as the replacement of negative unforgiving emotions …

[HTML][HTML] Characteristics of SARS-CoV-2 variants of concern B. 1.1. 7, B. 1.351 or P. 1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021

…, A Garcia-Leon, F Crispie, L O'Connor… - …, 2021 - eurosurveillance.org
We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436
B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-…

[HTML][HTML] Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing

…, D Griffiths, A Vaughan, L O'Connor… - … England Journal of …, 2013 - Mass Medical Soc
Background It has been thought that Clostridium difficile infection is transmitted predominantly
within health care settings. However, endemic spread has hampered identification of …