The minimum pharmacophore for activation of the human α 7 nicotinic acetylcholine receptor
(nAChR) is the tetramethylammonium cation. Previous work demonstrated that larger …

We introduce the term ‘silent agonists’ to describe ligands that can place the α7 nicotinic
acetylcholine receptor (nAChR) into a desensitized state with little or no apparent activation of …

We report a new method for constructing the ABC ring system of strigolactones, in a single
step from a simple linear precursor by acid-catalyzed double cyclization. The reaction …

Two series of novel 4-chlorophenyl N-alkyl phosphoramidates of 3′-O-(t-butoxycarbonyl)-5-fluoro-2′-deoxyuridine
(3′-BOC-FdU) (9a–9j) and 5-fluoro-2′-deoxyuridine (FdU) (10a–…

Średniowieczne zamki we Włoszech I castelli medievali in Italia O tłumaczeniach, kinie i
baśniach słów kilka In poche paro Page 1 ItaliAMO periodyk popularnonaukowy Studenckiego …

The first part of this dissertation is focused on the design and synthesis of molecules that
differentially regulate activation and desensitization of the human alpha7 nicotinic acetylcholine …

Homomeric α7 nicotinic acetylcholine receptors (nAChRs) have been suggested as an
important drug target for Alzheimer's Diseases, schizophrenia and inflammatory disorders. This …

… Kinga Chojnacka. The diversity of research in the Horenstein Lab attracts many exceptional
graduate students and exchange students, and it has been an honor to work alongside such …