In vitro and in vivo antioxidant properties of chlorogenic acid and caffeic acid

…, M Kobayashi, T Hirano, M Sugawara, K Iseki - International journal of …, 2011 - Elsevier
Dietary polyphenols are thought to be beneficial for human health as antioxidants. Coffee
beans contain a common polyphenol, chlorogenic acid. Chlorogenic acid is the ester of caffeic …

Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants

H Yoshioka, K Iseki, K Fujita - Pediatrics, 1983 - publications.aap.org
The development of stool bacterial flora was studied in breast-fed and bottle-fed infants. In
both groups of infants, the intestine was first colonized with enterobacteria and their number …

Transport function, regulation, and biology of human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4)

M Kobayashi, K Narumi, A Furugen, K Iseki - Pharmacology & Therapeutics, 2021 - Elsevier
Human monocarboxylate transporter 1 (hMCT1) and 4 (hMCT4) are involved in the proton-dependent
transport of monocarboxylates such as L-lactate, which play an essential role in …

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

…, K Tatsumi, M Ogata, S Kanemoto, K Otori, K Iseki… - Nature cell …, 2005 - nature.com
Endoplasmic reticulum (ER) stress transducers IRE1, PERK and ATF6 are well known to
transduce signals from the ER to the cytoplasm and nucleus when unfolded proteins are …

In vitro and in vivo antioxidant properties of ferulic acid: a comparative study with other natural oxidation inhibitors

…, Y Saito, S Oikawa, M Kobayashi, T Hirano, K Iseki - Food Chemistry, 2009 - Elsevier
Ferulic acid exhibits a wide range of therapeutic effects that are attributed to its potent
antioxidant capacity. However, in vitro antioxidant properties of ferulic acid have not been …

Improving the oral bioavailability of albendazole in rabbits by the solid dispersion technique

…, Y Yamayoshi, HE Xin, KEN Iseki… - Journal of pharmacy …, 1999 - Wiley Online Library
We have investigated the oral bioavailability of granules of albendazole, a drug used for
treating echinococcosis in man, prepared by the solid dispersion technique. Rapid dissolution …

[HTML][HTML] β-Lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

…, DP Rajan, AL Carter, M Sugawara, K Iseki… - Journal of Biological …, 2000 - ASBMB
Therapeutic use of cephaloridine, a β-lactam antibiotic, in humans is associated with
carnitine deficiency. A potential mechanism for the development of carnitine deficiency is …

Slit and glypican‐1 mRNAs are coexpressed in the reactive astrocytes of the injured adult brain

S Hagino, K Iseki, T Mori, Y Zhang, T Hikake, S Yokoya… - Glia, 2003 - Wiley Online Library
The slit family serves as a repellent for growing axons toward correct targets during neural
development. A recent report describes slit mRNAs expressed in various brain regions in …

[HTML][HTML] Inhibitory effects of lutein on endotoxin-induced uveitis in Lewis rats

…, Y Koyama, K Yoshida, I Ilieva, K Iseki… - … & visual science, 2006 - iovs.arvojournals.org
purpose. Lutein deposits in the macula and lens of human eyes with high concentration and
is well known as an eye-protective nutrient for its beneficial effects on eye disease such as …

Megalin contributes to kidney accumulation and nephrotoxicity of colistin

…, J Ogura, M Kobayashi, T Yamada, K Iseki - Antimicrobial agents …, 2013 - Am Soc Microbiol
Interest has recently been shown again in colistin because of the increased prevalence of
infections caused by multidrug-resistant Gram-negative bacteria. Although the potential for …