Effect of (R)-2-(2-aminothiazol-4-yl)-4′-{2-[(2-hydroxy-2-phenylethyl) amino] ethyl} acetanilide (YM178), a novel selective β3-adrenoceptor agonist, on bladder …
…, I Nagase, T Maruyama, M Sasamata, K Miyata… - … of Pharmacology and …, 2007 - ASPET
We evaluated the pharmacological characteristics of (R)-2-(2-aminothiazol-4-yl)-4′-{2-[(2-hydroxy-2-phenylethyl)amino]-ethyl}
acetanilide (YM178). YM178 increased cyclic AMP …
acetanilide (YM178). YM178 increased cyclic AMP …
M3 receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland
K Ikeda, S Kobayashi, M Suzuki, K Miyata… - Naunyn-Schmiedeberg's …, 2002 - Springer
The antimuscarinic profile of the experimental drug solifenacin/YM905 [(+)-(1S,3′R)-quinuclidin-3′-yl
1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate] for the treatment of …
1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate] for the treatment of …
In vitro and in vivo tissue selectivity profile of solifenacin succinate (YM905) for urinary bladder over salivary gland in rats
…, S Kobayashi, K Ikeda, S Sato, K Miyata… - European journal of …, 2004 - Elsevier
Solifenacin succinate [YM905; (+)-(1S,3′R)-quinuclidin-3′-yl 1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
monosuccinate] is a new muscarinic receptor antagonist …
monosuccinate] is a new muscarinic receptor antagonist …
Compounds possessing 5-HT3 receptor antagonistic activity inhibit intestinal propulsion in mice
…, Y Naitoh, T Kamato, M Yamano, K Miyata - European journal of …, 1996 - Elsevier
The role of 5-HT 3 receptors in the control of intestinal propulsive activity was investigated in
mice by a simple method in which the time taken for excretion of the head of an orally …
mice by a simple method in which the time taken for excretion of the head of an orally …
Bone regeneration by recombinant human bone morphogenetic protein-2 and a novel biodegradable carrier in a rabbit ulnar defect model
…, S Fukushima, K Nozaki, K Takahashi, K Miyata - Biomaterials, 2003 - Elsevier
The effects of recombinant human bone morphogenetic protein (rhBMP)-2 and a novel
carrier, PLGA-coated gelatin sponge (PGS), on bone defect repair was examined. A 1.5cm …
carrier, PLGA-coated gelatin sponge (PGS), on bone defect repair was examined. A 1.5cm …
[HTML][HTML] Biological deep temperature imaging with fluorescence lifetime of rare-earth-doped ceramics particles in the second NIR biological window
T Chihara, M Umezawa, K Miyata, S Sekiyama… - Scientific reports, 2019 - nature.com
Contactless thermal imaging generally relies on mid-infrared cameras and fluorescence
imaging with temperature-sensitive phosphors. Fluorescent thermometry in the near-infrared (…
imaging with temperature-sensitive phosphors. Fluorescent thermometry in the near-infrared (…
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents
…, M Suzuki, S Sato, M Sasamata, K Miyata - Biological and …, 2007 - jstage.jst.go.jp
MATERIALS AND METHODS Materials Solifenacin succinate (YM905, Vesicare®), tolterodine
tartrate, darifenacin and propiverine hydrochloride were prepared by Astellas Pharma Inc.…
tartrate, darifenacin and propiverine hydrochloride were prepared by Astellas Pharma Inc.…
Role of the serotonin3 receptor in stress-induced defecation.
K Miyata, T Kamato, A Nishida, H Ito, H Yuki… - … of Pharmacology and …, 1992 - ASPET
The possibility that 5-hydroxytryptamine (serotonin; 5-HT) mediates bowel dysfunction
caused by stress was evaluated in rats and mice treated with 5-HT or thyrotropin-releasing …
caused by stress was evaluated in rats and mice treated with 5-HT or thyrotropin-releasing …
(3R)-N-(1-(tert-Butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H- 1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): A Potent and Orally …
…, M Satoh, A Nishida, S Akuzawa, K Miyata - Journal of medicinal …, 1997 - ACS Publications
A number of new 1,4-benzodiazepin-2-one-based gastrin/CCK-B receptor antagonists
related to the archetypal analogue L-365,260, and more closely to the recently reported …
related to the archetypal analogue L-365,260, and more closely to the recently reported …
Involvement of the 5-HT3 receptor in CRH-induced defecation in rats
K Miyata, H Ito, S Fukudo - American Journal of Physiology …, 1998 - journals.physiology.org
We evaluated the possibility that serotonin (5-HT) mediates defecation induced by
corticotropin-releasing hormone (CRH) exogenously administered or released from the central …
corticotropin-releasing hormone (CRH) exogenously administered or released from the central …