We describe five cases of segmental arterial mediolysis (SAM), formerly known as segmental
mediolytic arteritis. SAM occurs in epicardial coronary arteries and in the abdominal …

Glyoxalase I (GLO I) is the rate-limiting enzyme for detoxification of methylglyoxal (MG), a side
product of glycolysis, which is able to induce apoptosis. Since GLO I is known to be highly …

Objective This post hoc analysis of six randomized, double-blind, Phase II and III studies
evaluated efficacy and safety of adjunctive perampanel (2–12 mg/day) in adolescent patients (…

Glyoxalase I (GLO I) is the rate-limiting enzyme for detoxification of methylglyoxal (MG), a
side-product of glycolysis, which is able to induce apoptosis. Since GLO I is known to be highly …

Background. Uterine lymphoma is a rare disease; therefore, information regarding histologic
type, immunophenotype of tumor cells, and etiologic factors are limited. Methods. Seven …

Clinical and pathologic findings in 19 cases of primary non-Hodgkin’s lymphoma of the
breast collected from several hospitals in Japan were reviewed. All patients were women (…

The human glyoxalase I (hGLO I), which is a rate-limiting enzyme in the pathway for detoxification
of apoptosis-inducible methylglyoxal (MG), has been expected as an attractive target …

MATERIALS AND METHODS Materials The mouse anti-total-tau (TAU-5), and rabbit anti-phospho-tau
(Ser396) antibodies were purchased from Biosource International (Camarillo, CA, …

Tyrosinase inhibitors are important agents for cosmetic products. We examined here the
inhibitory effects of three isomers of thujaplicins (α, β and γ) on mushroom tyrosinase and …

Purpose To evaluate long-term tolerability, safety and efficacy of adjunctive perampanel in a
Phase II, multicentre, open-label, dose-ascending Study 231 (NCT00849212) and its …