Vitamin D and periodontal disease

Y Amano, K Komiyama, M Makishima - Journal of oral science, 2009 - jstage.jst.go.jp
1, 25-Dihydroxyvitamin D3 [1, 25 (OH) 2D3; 1, 25-dihydroxycholecalciferol or calcitriol] is
the active form of vitamin D3, a lipid-soluble vitamin that plays a role in calcium and bone …

Polymeric immunoglobulin receptor

M Asano, K Komiyama - Journal of oral science, 2011 - jstage.jst.go.jp
The surface of mucosal sites, such as the intestinal tract, are covered by epithelial cells. To
protect the intestinal environment from invading pathogens and maintain homeostasis, the …

Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham …

…, J Khitha, H Kikushima, T Kobayashi, K Komiyama… - The Lancet, 2020 - thelancet.com
Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL Pivotal…

[HTML][HTML] Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation

…, M Tezuka, Y Kosuge, K Ishige, Y Ito, K Komiyama… - PloS one, 2011 - journals.plos.org
A link between circadian rhythm and metabolism has long been discussed. Circadian rhythm
is controlled by positive and negative transcriptional and translational feedback loops …

Denture wearing during sleep doubles the risk of pneumonia in the very elderly

…, N Hirose, N Gionhaku, K Komiyama - Journal of dental …, 2015 - journals.sagepub.com
Poor oral health and hygiene are increasingly recognized as major risk factors for pneumonia
among the elderly. To identify modifiable oral health–related risk factors, we prospectively …

Convolutamydine A, a novel bioactive hydroxyoxindole alkaloid from marine bryozoan Amathia convoluta

Y Kamano, H Zhang, Y Ichihara, H Kizu, K Komiyama… - Tetrahedron letters, 1995 - Elsevier
Convolutamydine A (1), a new alkaloid containing a dibromohydroxyoxindole moiety, was
isolated from the Floridian bryozoan Amathia convoluta and the structure was elucidated on …

Biologically Active Indole Alkaloids from Kopsia arborea

KH Lim, O Hiraku, K Komiyama, T Koyano… - Journal of natural …, 2007 - ACS Publications
… A total of 50 alkaloids (see Experimental Section) were thus obtained from the present
investigation of the stem-bark extract of the Malayan K. arborea. Of these, several, such as …

Biologically Active Aspidofractinine, Rhazinilam, Akuammiline, and Vincorine Alkaloids from Kopsia

…, M Hayashi, T Koyano, K Komiyama… - Journal of natural …, 2007 - ACS Publications
… of new indole alkaloids from K. singapurensis. An early study … , initial examination indicated
that it was K. teoi. Accordingly we … paper can now therefore be attributed to K. singapurensis. …

Maximum occlusal force and physical performance in the oldest old: the Tokyo oldest old survey on total health

…, T Takebayashi, T Iwase, K Komiyama… - Journal of the …, 2012 - Wiley Online Library
Objectives To elucidate the independent relationship between masticatory and physical
performance in community‐living oldest old people (mean age ± standard deviation 87.8 ± 2.2, …

Total synthesis of (+)-madindoline A and (−)-madindoline B, potent, selective inhibitors of interleukin 6. Determination of the relative and absolute configurations

…, Y Harigaya, M Hayashi, K Komiyama… - Journal of the …, 2000 - ACS Publications
Interleukin 6 (IL-6), a multifunctional cytokine, plays a central regulatory role in host defense
mechanisms. 1 However, in tumor cells IL-6 stimulates cell proliferation in an autocrine/…