The kappa opioid agonist U-50,488 H antagonizes respiratory effects of mu opioid receptor agonists in conscious rats
K Dosaka-Akita, FC Tortella, JW Holaday… - … of Pharmacology and …, 1993 - apps.dtic.mil
… Mo rphtine sulfate and 11 -St A SMI were k ind lY d mat !'d 1)x Dr. John 1). Minnla (National
Cancer Institute, Bethesda, MlD) and … Dosaka-Akita et al. … K., I1t,011, 11. I ANtD IP.F, N. …
Cancer Institute, Bethesda, MlD) and … Dosaka-Akita et al. … K., I1t,011, 11. I ANtD IP.F, N. …
CD4+ T cells in cancer stroma, not CD8+ T cells in cancer cell nests, are associated with favorable prognosis in human non‐small cell lung cancers
…, I Kinoshita, S Ogura, H Dosaka‐Akita… - Cancer …, 2003 - Wiley Online Library
We investigated intratumoral tumor‐infiltrating lymphocytes (TILs), including CD4 + and
CD8 + T cells, in non‐small cell lung cancers (NSCLCs) and their relationships with …
CD8 + T cells, in non‐small cell lung cancers (NSCLCs) and their relationships with …
Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers
…, MA Gyamfi, M Sakurai, H Dosaka-Akita… - …, 2004 - academic.oup.com
We reported previously that subjects homozygous for the cytochrome P450 2A6 ( CYP2A6 )
* 4 have a lower risk of lung cancer. The purpose of this study was to clarify whether or not …
* 4 have a lower risk of lung cancer. The purpose of this study was to clarify whether or not …
Multiplex gene‐panel testing for lung cancer patients
…, M Mikubo, T Yokose, H Dosaka‐Akita - Pathology …, 2020 - Wiley Online Library
The year 2019 was considered to be the first year of cancer genome medicine in Japan,
with three gene‐panel tests using next‐generation sequencing (NGS) techniques being …
with three gene‐panel tests using next‐generation sequencing (NGS) techniques being …
Overexpression of the Aldo-Keto Reductase Family Protein AKR1B10 Is Highly Correlated with Smokers' Non–Small Cell Lung Carcinomas
…, M Nishimura, M Fukayama, H Dosaka-Akita… - Clinical cancer …, 2005 - AACR
… Note that these metaplastic regions are observed successively in noncancerous regions of
a case with SCC (K). LN, subcellular localization of endogenous AKR1B10 in A549 cells in 70…
a case with SCC (K). LN, subcellular localization of endogenous AKR1B10 in A549 cells in 70…
The coordinated actions of TIM-3 on cancer and myeloid cells in the regulation of tumorigenicity and clinical prognosis in clear cell renal cell carcinomas
…, S Suzu, I Kinoshita, H Dosaka-Akita, K Akashi… - Cancer immunology …, 2015 - AACR
Clear cell renal cell carcinoma (ccRCC) is one of most common cancers in urogenital
organs. Although recent experimental and clinical studies have shown the immunogenic …
organs. Although recent experimental and clinical studies have shown the immunogenic …
Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy
…, M Matsushita, H Dosaka-Akita, K Miyasaka - International Journal of …, 2003 - Elsevier
PURPOSE: To examine the feasibility and reliability of insertion of internal fiducial markers
into various organs for precise setup and real-time tumor tracking in radiotherapy (RT). …
into various organs for precise setup and real-time tumor tracking in radiotherapy (RT). …
B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression
…, K Yamazaki, M Azuma, I Kinoshita, H Dosaka-Akita… - Clinical cancer …, 2004 - AACR
Purpose: B7-H1/PD-L1 (B7-H1) and B7-DC/PD-L2 (B7-DC) are ligands for the receptor PD-1,
which is known to negatively regulate T-cell activation. In the present study, we …
which is known to negatively regulate T-cell activation. In the present study, we …
Expression and alteration of ras and p53 proteins in patients with lung carcinoma accompanied by idiopathic pulmonary fibrosis
…, A Kamachi‐Satoh, H Dosaka‐Akita… - … Journal of the …, 2002 - Wiley Online Library
… Expression of ras protein in type II alveolar pneumocytes and mutation in the codon 12 of
K‐ras gene in lung tissue may contribute to the induction of lung carcinoma in patients with IPF. …
K‐ras gene in lung tissue may contribute to the induction of lung carcinoma in patients with IPF. …
Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy
…, S Ogura, H Dosaka-Akita, K Miyasaka… - International Journal of …, 2005 - Elsevier
Purpose: Internal 1.5-mm fiducial markers were used in real-time tumor-tracking radiotherapy
(RT) for lung cancer. The fixation rate of the markers using the bronchial insertion …
(RT) for lung cancer. The fixation rate of the markers using the bronchial insertion …