Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors

FE Harrell Jr, KL Lee, DB Mark - Statistics in medicine, 1996 - Wiley Online Library
Multivariable regression models are powerful tools that are used frequently in studies of clinical
outcomes. These models can use a mixture of categorical and continuous variables and …

Regression models in clinical studies: determining relationships between predictors and response

FE Harre Jr, KL Lee, BG Pollock - JNCI: Journal of the National …, 1988 - academic.oup.com
Multtiple regression models are increasingly being applied to clinical studies. Such models
are powerful analytic tools that yields valid statistical inferences and make reliable …

Generating specificity and diversity in the transcriptional response to hypoxia

U Lendahl, KL Lee, H Yang, L Poellinger - Nature Reviews Genetics, 2009 - nature.com
The sensing of oxygen levels and maintenance of oxygen homeostasis is crucial for cells.
The hypoxic-sensitive regulation of gene expression allows information about the oxygen …

[HTML][HTML] Amiodarone or an implantable cardioverter–defibrillator for congestive heart failure

GH Bardy, KL Lee, DB Mark, JE Poole… - … England Journal of …, 2005 - Mass Medical Soc
Background Sudden death from cardiac causes remains a leading cause of death among
patients with congestive heart failure (CHF). Treatment with amiodarone or an implantable …

An introduction to logistic regression analysis and reporting

CYJ Peng, KL Lee, GM Ingersoll - The journal of educational …, 2002 - Taylor & Francis
The purpose of this article is to provide researchers, editors, and readers with a set of guidelines
for what to expect in an article using logistic regression techniques. Tables, figures, and …

Evaluating the yield of medical tests

FE Harrell, RM Califf, DB Pryor, KL Lee, RA Rosati - Jama, 1982 - jamanetwork.com
… McNeer JF, Margolis JR, Lee KL, et al: The role of the exercise test in the evaluation of patients
… Harris PJ, Harrell FE, Lee KL, et al: Survival in medically treated coronary artery disease. …

[HTML][HTML] A randomized study of the prevention of sudden death in patients with coronary artery disease

AE Buxton, KL Lee, JD Fisher… - … England Journal of …, 1999 - Mass Medical Soc
Background Empirical antiarrhythmic therapy has not reduced mortality among patients with
coronary artery disease and asymptomatic ventricular arrhythmias. Previous studies have …

Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial

CM O'Connor, DJ Whellan, KL Lee, SJ Keteyian… - Jama, 2009 - jamanetwork.com
Context Guidelines recommend that exercise training be considered for medically stable
outpatients with heart failure. Previous studies have not had adequate statistical power to …

Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for …

…, AJ Greenspon, RA Freedman, KL Lee… - Circulation, 2003 - Am Heart Assoc
Background— Dual-chamber (DDDR) pacing preserves AV synchrony and may reduce
heart failure (HF) and atrial fibrillation (AF) compared with ventricular (VVIR) pacing in sinus …

[HTML][HTML] Rhythm control versus rate control for atrial fibrillation and heart failure

…, S Nattel, DG Wyse, P Dorian, KL Lee… - … England Journal of …, 2008 - Mass Medical Soc
Background It is common practice to restore and maintain sinus rhythm in patients with atrial
fibrillation and heart failure. This approach is based in part on data indicating that atrial …