β-Adrenergic receptors (β-ARs) are members of the superfamily of G-protein-coupled
receptors that mediate the effects of catecholamines in the sympathetic nervous system. Three …

At least three distinct beta-adrenergic receptor (beta-AR) subtypes exist in mammals. These
receptors modulate a wide variety of processes, from development and behavior, to cardiac …

Manipulations of the murine genome that alter cardiovascular function have created the need
for methods to study cardiovascular physiology in genetically altered animals in vivo. We …

Background Trauma is the number one killer of individuals 1–44 y of age in the United States.
The prognosis and treatment of inflammatory complications in critically injured patients …

Simulations using empirical inter-atomic potentials have been used to predict the change in
volume of the uranium dioxide lattice due to the accommodation of soluble fuel additives …

β 1 -Adrenergic receptors (β 1 -ARs) are key targets of sympathetic nervous system activity
and play a major role in the beat-to-beat regulation of cardiac chronotropy and inotropy. We …

A growing number of modern scientific problems in areas such as genomics, neurobiology,
and spatial epidemiology involve the measurement and analysis of thousands of related …

Background: Pregnancy is associated with profound cardiovascular adaptation with altered
cardiac autonomic balance. It can be studied by heart rate variability (HRV) which indicates …

Deficiency of phospholamban (PLB) results in enhancement of basal murine cardiac
function and an attenuated response to β-adrenergic stimulation. To determine whether the …

The role of cytoskeletal microtubules and microfilaments in modulating cAMP generation in
S49 lymphoma cells was investigated using the agents colchicine and cytochalasin B, …