The emerging plasticity of SARS-CoV-2

KD McCormick, JL Jacobs, JW Mellors - Science, 2021 - science.org
Viruses evolve as a result of mutation (misincorporations, insertions or deletions, and
recombination) and natural selection for favorable traits such as more efficient viral replication, …

Intractable coronavirus disease 2019 (COVID-19) and prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in a chimeric antigen …

…, ME Agha, JW Mellors, KD McCormick… - Clinical Infectious …, 2021 - academic.oup.com
A chimeric antigen receptor-modified T-cell therapy recipient developed severe coronavirus
disease 2019, intractable RNAemia, and viral replication lasting >2 months. Premortem …

Neurotoxic acylpolyamines from spider venoms

KD McCormick, J Meinwald - Journal of chemical ecology, 1993 - Springer
In their relations with humans, spiders have acquired considerable respect, often inspiring
emotions ranging from mild discomfort to genuine terror. 1-3 One of the few literary instances …

Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma

KD McCormick, A Ghosh, S Trivedi, L Wang… - …, 2016 - academic.oup.com
Head and neck squamous cell carcinoma (HNSCC) is a devastating disease for which new
treatments, such as immunotherapy are needed. Synthetic double-stranded RNAs, which …

Human apolipoprotein E peptides inhibit hepatitis C virus entry by blocking virus binding

S Liu, KD McCormick, W Zhao, T Zhao, D Fan… - Hepatology, 2012 - journals.lww.com
Hepatitis C virus (HCV) entry is a multiple-step process involving a number of host factors
and hence represents a promising target for new antiviral drug development. In search of …

Antibody responses after mRNA-based COVID-19 vaccination in residential older adults: implications for reopening

…, MD Sobolewski, PN Enick, KD McCormick… - Journal of the American …, 2021 - Elsevier
Objective COVID-19 disproportionately impacts residents in long-term care facilities. Our
objective was to quantify the presence and magnitude of antibody response in vaccinated, …

Diel foraging patterns of male euglossine bees: ecological causes and evolutionary responses by plants

WS Armbruster, KD McCormick - Biotropica, 1990 - JSTOR
Male euglossine bees (Euglossa, Eulaema, Exaerete) were censused at regular intervals at
chemical baits in Surinam, Trinidad, and Costa Rica. Fragrance foraging was initiated at ca …

Therapy With Allogeneic Severe Acute Respiratory Syndrome Coronavirus-2–Specific T Cells for Persistent Coronavirus Disease 2019 in Immunocompromised …

…, A Heaps, U Parikh, KD McCormick… - Clinical Infectious …, 2023 - academic.oup.com
We administered severe acute respiratory syndrome coronavirus-2 viral-specific T cells (VSTs)
under emergency investigational new drug applications to 6 immunocompromised …

Azamacrolides: a family of alkaloids from the pupal defensive secretion of a ladybird beetle (Epilachna varivestis).

AB Attygalle, KD McCormick… - Proceedings of the …, 1993 - National Acad Sciences
Defensive droplets from glandular hairs of the pupa of the Mexican bean beetle, Epilachna
varivestis, contain a group of structurally novel alkaloids, the azamacrolides. The major …

Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production

…, J Perez, Z Chong, S Nair, L So, KD McCormick… - Immunity, 2024 - cell.com
In response to viral infection, how cells balance translational shutdown to limit viral replication
and the induction of antiviral components like interferons (IFNs) is not well understood. …