Central sensitization of dorsal root potentials and dorsal root reflexes: An in vitro study in the mouse spinal cord.

J VicenteBaz, JA Lopez‐Garcia… - … Journal of Pain, 2022 - Wiley Online Library
Background Axo‐axonic contacts onto central terminals of primary afferents modulate
sensory inputs to the spinal cord. These contacts produce primary afferent depolarization (PAD), …

Effects of novel subtype selective M-current activators on spinal reflexes in vitro: Comparison with retigabine

J Vicente-Baz, JA Lopez-Garcia, I Rivera-Arconada - Neuropharmacology, 2016 - Elsevier
The activation of Kv7 channels and the resulting M-current is a powerful mechanism to control
neuronal excitability with profound effects in pain pathways. Despite the lack of specific …

[HTML][HTML] Targeting Kv7 channels in pain pathways

I Rivera-Arconada, J Vicente-Baz, JA Lopez-Garcia - Oncotarget, 2017 - ncbi.nlm.nih.gov
The Kv7 family of potassium channels, formerly known as KCNQ, is composed of five members
numbered from 1 to 5. Kv7 subunits 2 to 5 are expressed in neurons where they give rise …

Implication of Kv7 channels in the spinal antinociceptive actions of celecoxib

J Vicente-Baz, JA Lopez-Garcia… - Journal of Pharmacology …, 2019 - ASPET
Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat pain
conditions in humans. In addition to its blocking activity on cyclooxygenase (COX) enzymes, …

Spinal actions of the NSAID diclofenac on nociceptive transmission in comparison to the Kv7 channel opener flupirtine

J Vicente-Baz, I Rivera-Arconada - Neuroscience, 2020 - Elsevier
NSAIDs are the drugs most commonly used to alleviate pain. Despite being a heterogeneous
group of compounds, all of them share a mechanism of action based on blockade of COXs …

Clinicopathological and molecular characterization of metastatic gastrointestinal stromal tumors with prolonged benefit to frontline imatinib

…, V Martínez‐Marín, D VicenteBaz… - The …, 2019 - academic.oup.com
Background Oncogenic KIT/PDGFRA signaling inhibition with imatinib achieves disease
control in most patients with advanced/metastatic gastrointestinal stromal tumor (GIST), but …

An open-label, multicenter, phase 2 study of the safety and efficacy of navtemadlin (KRT-232) in patients with TP53 wild-type relapsed/refractory small cell lung …

…, S Hiret, A Rittmeyer, S Sukumaran, D Vicente Baz… - 2022 - ascopubs.org
TPS8600 Background: Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine
tumor characterized by early metastasis and a high recurrence rate with currently available …

[HTML][HTML] Five-year survival outcomes from the PACIFIC trial: durvalumab after chemoradiotherapy in stage III non–small-cell lung cancer

DR Spigel, C Faivre-Finn, JE Gray… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
PURPOSE The phase III PACIFIC trial compared durvalumab with placebo in patients with
unresectable, stage III non–small-cell lung cancer and no disease progression after …

[BOOK][B] Liber magnificarum (1607)

S de Vivanco - 2020 - books.google.com
The Spanish composer Sebastián de Vivanco (ca. 1551–1622) was born, like his revered
contemporary Tomás Luis de Victoria, in Avila. Having secured prestigious cathedral and …

[HTML][HTML] Trabajo Original Study on the nutritional status and feeding habits in school-children in Madrid city (Spain) during the economic crisis

JMM Villares, MS De Pipaón, ÁC Sanz, JJD Martín… - 2018 - nutricionhospitalaria.org
Introduction: the recent economic and financial crisis has affected most Western countries,
especially families of low socioeconomic classes. We speculate that worsening of …