Sequential Ugi/Heck cyclization strategies for the facile construction of highly functionalized N-heterocyclic scaffolds

V Gracias, JD Moore, SW Djuric - Tetrahedron letters, 2004 - Elsevier
A new strategy employing an Ugi four-component reaction and a microwave-assisted
intramolecular Heck cyclization in a sequential fashion to access an array of N-containing …

Human-scale economics: economic growth and poverty reduction in Northeastern Thailand

JD Moore, JA Donaldson - World Development, 2016 - Elsevier
Under what conditions does economic growth benefit the poor? One way to answer this
question is to identify and compare positive and negative outlier areas, those that experience …

Pharmacological characterization of IW-1973, a novel soluble guanylate cyclase stimulator with extensive tissue distribution, antihypertensive, anti-inflammatory, and …

…, K Tang, GYJ Im, J Sheppeck, JD Moore… - … of Pharmacology and …, 2018 - ASPET
Soluble guanylate cyclase (sGC), a key signal-transduction enzyme, increases the conversion
of guanosine-5′-triphosphate to cGMP upon binding of nitric oxide (NO). Endothelial …

Multivalent activation in temporary phosphate tethers: A new tether for small molecule synthesis

A Whitehead, MD McReynolds, JD Moore… - Organic …, 2005 - ACS Publications
A new tether for small molecule synthesis is reported. This functionally active tether mediates
the desymmetrization of a pseudo-C 2 -symmetric tris-allylic phosphate triester to generate …

ROMP-generated oligomeric sulfonyl chlorides as versatile soluble scavenging agents

JD Moore, RH Herpel, JR Lichtsinn, DL Flynn… - Organic …, 2003 - ACS Publications
A new method for homogeneous nucleophilic scavenging employing oligomeric sulfonyl
chloride (OSC) reagents is described. The method utilizes OSC to rapidly scavenge a variety of …

Ring-closing metathesis strategies to cyclic sulfamide peptidomimetics

JM Dougherty, DA Probst, RE Robinson, JD Moore… - Tetrahedron, 2000 - Elsevier
Ring-closing metathesis (RCM) strategies toward the synthesis of a number of constrained
sulfamides are discussed. This approach exploits the inherent chemistry of sulfamides and …

Conformationally constrained α-Boc-aminophosphonates via transition Metal-Catalyzed/Curtius rearrangement strategies

JD Moore, KT Sprott, PR Hanson - The Journal of Organic …, 2002 - ACS Publications
A transition metal-catalyzed/Curtius rearrangement sequence toward the development of
conformationally constrained α-Boc-aminophosphonates 2−6 is described. An approach using …

Synthesis of novel fused isoxazoles and isoxazolines by sequential Ugi/INOC reactions

I Akritopoulou-Zanze, V Gracias, JD Moore, SW Djuric - Tetrahedron letters, 2004 - Elsevier
We report the synthesis of novel fused isoxazoles and isoxazolines by employing an
unprecedented Ugi/INOC synthetic sequence. The coupling of the Ugi multicomponent reaction …

A convenient approach to cyclic enol phosphates via ring-closing metathesis

A Whitehead, JD Moore, PR Hanson - Tetrahedron letters, 2003 - Elsevier
A strategy employing the second generation Grubbs catalyst in order to facilitate the
generation of a variety of cyclic enol phosphates, including 2H-chromen-4-yl, 1,2-dihydroquinolin-4-…

Going green in Thailand: Upgrading in global organic value chains

JD Moore, JA Donaldson - Journal of Agrarian Change, 2023 - Wiley Online Library
Under what conditions are some small‐scale agricultural producers able to overcome challenges
associated with shifting to organic production, whereas most are not? The answers are …