Antidiabetic Effects of Panax ginseng Berry Extract and the Identification of an Effective Component

AS Attele, YP Zhou, JT Xie, JA Wu, L Zhang, L Dey… - Diabetes, 2002 - Am Diabetes Assoc
We evaluated antihyperglycemic and anti-obese effects of Panax ginseng berry extract and
its major constituent, ginsenoside Re, in obese diabetic C57BL/6J ob/ ob mice and their lean …

Antioxidant effects of ginsenoside Re in cardiomyocytes

JT Xie, ZH Shao, TLV Hoek, WT Chang, J Li… - European journal of …, 2006 - Elsevier
We have previously demonstrated that American ginseng berry extract exhibited significant
protection against oxidant-mediated injury in cardiomyocytes. To extend this work, we sought …

[HTML][HTML] Anti-diabetic effect of ginsenoside Re in ob/ob mice

JT Xie, SR Mehendale, X Li, R Quigg, X Wang… - … et Biophysica Acta (BBA …, 2005 - Elsevier
We evaluated the anti-diabetic effects of ginsenoside Re in adult male C57BL/6J ob/ob mice.
Diabetic ob/ob mice with fasting blood glucose levels of approximately 230 mg/dl received …

Steamed American ginseng berry: ginsenoside analyses and anticancer activities

…, A Wang, M Ni, X Luo, HH Aung, JT Xie… - Journal of Agricultural …, 2006 - ACS Publications
This study was designed to determine the changes in saponin content in American ginseng
berries after treatment by heating and to assess the anticancer effects of the extracts. After …

The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity

…, S Mehendale, Y Xiao, HH Aung, JT Xie… - Anesthesia & …, 2004 - journals.lww.com
IMPLICATIONS: Valerian is an herb used in treating anxiety and insomnia. We observed
that the valerian effects are mediated through brain gamma-aminobutyric acid (GABA) …

Ginseng and diabetes

JT Xie, S Mehendale, CS Yuan - The American journal of Chinese …, 2005 - World Scientific
Ginseng is a well-known medicinal plant used in traditional Oriental medicine. In recent
decades, ginseng root has gained popularity as a dietary supplement in the United States. …

American ginseng leaf: ginsenoside analysis and hypoglycemic activity

JT Xie, SR Mehendale, A Wang, AH Han, JA Wu… - Pharmacological …, 2004 - Elsevier
Previous studies showed that both American ginseng root and American ginseng berry
extracts possess hypoglycemic properties. In this study, we investigated whether American …

Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells

…, B Zhang, WX Song, M Ni, S Mehendale, JT Xie… - Cancer chemotherapy …, 2007 - Springer
Purpose Panax notoginseng is a commonly used Chinese herb. Although a few studies have
found that notoginseng shows anti-tumor effects, the effect of this herb on colorectal cancer …

Anti-diabetic effects of Gymnema yunnanense extract

JT Xie, A Wang, S Mehendale, J Wu, HH Aung… - Pharmacological …, 2003 - Elsevier
In this study, we evaluated anti-hyperglycemic effect and body weight reduction activity of
Gymnema yunnanense extract in obese ob/ob and diabetic db/db mice. Animals received daily …

Antihyperglycemic effects of total ginsenosides from leaves and stem of Panax ginseng

J XIE, C WANG, A WANG, J Wu… - Acta Pharmacologica …, 2005 - Wiley Online Library
Aim: The antihyperglycemic effects of the total ginsenosides in Chinese ginseng (TGCG),
extracted from leaves and the stem, were evaluated in diabetic C57BL/6J ob/ob mice. Methods: …