User profiles for Jerry M. Farley
Jerry M FarleyProfessor of Pharmacology and Toxicology, University of Mississippi Medical Center Verified email at umc.edu Cited by 2077 |
[HTML][HTML] Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport
H Liu, JM Farley - BMC pharmacology, 2005 - Springer
Background The first generation antihistamines, such as diphenhydramine, are fairly potent
muscarinic antagonists in addition to being H1 selective antihistamines. The antimuscarinic …
muscarinic antagonists in addition to being H1 selective antihistamines. The antimuscarinic …
[HTML][HTML] Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's …
…, Z He, A Pani, P Kyle, X Ou, T Mosley, JM Farley… - PLoS …, 2012 - journals.plos.org
Restorative/protective therapies to restore dopamine neurons in the substantia nigra pars
compacta (SNpc) are greatly needed to effectively change the debilitating course of …
compacta (SNpc) are greatly needed to effectively change the debilitating course of …
Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease
C Sun, X Ou, JM Farley, C Stockmeier… - Current Alzheimer …, 2012 - ingentaconnect.com
More than a third of Alzheimer’s disease (AD) patients show nigrostriatal pathway disturbances,
resulting in akinesia (inability to initiate movement) and bradykinesia (slowness of …
resulting in akinesia (inability to initiate movement) and bradykinesia (slowness of …
Cardiodepressant and neurologic actions of Solenopsis invicta (imported fire ant) venom alkaloids
G Howell, J Butler, RD Deshazo, JM Farley… - Annals of Allergy …, 2005 - Elsevier
BACKGROUND: We hypothesized that the alkaloid compounds that are the majority
components of fire ant (Solenopsis invicta) venom are capable of producing cardiovascular and …
components of fire ant (Solenopsis invicta) venom are capable of producing cardiovascular and …
Cardiac toxicity of some echinocandin antifungals
Background: Unexplained cardiovascular decompensation has been observed during central
venous administration of some echinocandins. Objective: The purpose of this study was to …
venous administration of some echinocandins. Objective: The purpose of this study was to …
Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells
WS Chung, JM Farley, A Swenson… - … of Physiology-Cell …, 2010 - journals.physiology.org
Recent studies suggest that certain acid-sensing ion channels (ASIC) are expressed in
vascular smooth muscle cells (VSMCs) and are required for VSMC functions. However, …
vascular smooth muscle cells (VSMCs) and are required for VSMC functions. However, …
Enhanced large conductance K+ channel activity contributes to the impaired myogenic response in the cerebral vasculature of Fawn Hooded Hypertensive rats
Recent studies have indicated that the myogenic response (MR) in cerebral arteries is
impaired in Fawn Hooded Hypertensive (FHH) rats and that transfer of a 2.4 megabase pair …
impaired in Fawn Hooded Hypertensive (FHH) rats and that transfer of a 2.4 megabase pair …
Antimuscarinic actions of antihistamines on the heart
H Liu, Q Zheng, JM Farley - Journal of Biomedical Science, 2006 - Springer
Antimuscarinic side-effects, which include dry mouth, tachycardia, thickening of mucus
possibly sedation, of the antihistamines limited the usefulness of these drugs. The advent of …
possibly sedation, of the antihistamines limited the usefulness of these drugs. The advent of …
[PDF][PDF] Acetylcholine-induced chloride current oscillations in swine tracheal smooth muscle cells.
X Liu, JM Farley - Journal of Pharmacology and Experimental …, 1996 - Citeseer
The activation of muscarinic receptors by acetylcholine(ACh) in tracheal smooth muscle cells
induced Ca oscillations, measured as the activation of Ca4”-dependent CI currents(Cl) at …
induced Ca oscillations, measured as the activation of Ca4”-dependent CI currents(Cl) at …
Frequency modulation of acetylcholine-induced oscillations in Ca++ and Ca (++)-activated Cl-current by cAMP in tracheal smooth muscle.
LC Nuttle, JM Farley - Journal of Pharmacology and Experimental …, 1996 - ASPET
The effects of adenosine 3':5'-cyclic monophosphate (cAMP) on acetylcholine (ACh)-induced
oscillations in intracellular calcium concentration ([Ca++]i) and Ca(++)-activated Cl- current …
oscillations in intracellular calcium concentration ([Ca++]i) and Ca(++)-activated Cl- current …