[HTML][HTML] 14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

S Lehoux, J Abe, JA Florian, BC Berk - Journal of Biological Chemistry, 2001 - ASBMB
Na + /H + exchanger isoform-1 (NHE1), the ubiquitous form of the Na + /H + exchanger, has
increased activity in hypertensive patients and in animal models of hypertension. …

Integration of mitogen-activated protein kinase kinase activation in vascular 5-hydroxytryptamine2A receptor signal transduction

JA Florian, SW Watts - Journal of Pharmacology and Experimental …, 1998 - ASPET
Vascular 5-Hydroxytryptamine 2A (5-HT 2A ) receptor signaling and contraction has been
associated with the activation of L-type calcium channels, phospholipase C (PLC) and, as we …

Epidermal growth factor: a potent vasoconstrictor in experimental hypertension

JA Florian, SW Watts - American Journal of Physiology …, 1999 - journals.physiology.org
We have tested the hypothesis that growth factor signaling pathways are augmented in
hypertension, a disease associated with vascular smooth muscle cell growth. Thoracic aorta was …

Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction

SW Watts, JA Florian, KM Monroe - Journal of Pharmacology and …, 1998 - ASPET
Angiotensin II (Ang II) is a potent pressor hormone, a stimulus for vascular smooth muscle
hypertrophy and an activator of multiple tyrosine kinases. The physiological effects of Ang II …

Arterial epidermal growth factor receptor expression in deoxycorticosterone acetate–salt hypertension

C Northcott, JA Florian, A Dorrance, SW Watts - Hypertension, 2001 - Am Heart Assoc
Epidermal growth factor (EGF) causes contraction in arteries from deoxycorticosterone acetate
(DOCA)–salt hypertensive rats but not in normotensive sham rats. We hypothesized that …

Mineralocorticoids upregulate arterial contraction to epidermal growth factor

JA Florian, A Dorrance, RC Webb… - American Journal of …, 2001 - journals.physiology.org
The present studies test the hypothesis that contraction to EGF is dependent on mineralocorticoids
and/or an elevation in systolic blood pressure (SBP). Endothelium-denuded thoracic …

Increased Epidermal Growth Factor Receptor Expression in Rat Aorta in Deoxycorticosterone Acetate-Salt Induced Hypertension/ATL

JJ Manteuffel, JA Florian, AN Dorrance, SW Watts - 2000 - Am Heart Assoc
79 Receptors and signal transduction Epidermal growth factor (EGF) causes contraction in
arteries from Deoxycorticosterone Acetate-Salt (DOCA) hypertensive rats but not in …

[BOOK][B] Pharmacologic, physiologic, and biochemical characterization of epidermal growth factor-induced contraction in experimental hypertension

JA Florian - 1999 - search.proquest.com
computer printer. Page 1 LGGLGLGGGGGGG GGG aaYLL This manuscript has been reproduced
from the microfilm master. UMI films the text directly from the original or copy submitted…

Insulin-like growth factor inhibits vascular contraction to 5-hydroxytryptamine: involvement of tyrosine phosphatase

A Melis, SW Watts, J Florian, S Klarr… - … : The Vascular System, 2000 - Elsevier
This study tests the hypothesis that insulin-like growth factor 1 (IGF-1)-induced vasodilation
is due to the stimulation of tyrosine phosphatase. Rat aortic segments (endothelium intact) …

COVID-19 in the Arctic: briefing document for senior arctic officials

A Council - 2020 - oaarchive.arctic-council.org
In March 2020, the World Health Organization (WHO) declared the outbreak of the novel
coronavirus disease a pandemic, bringing drastic changes to people’s lives overnight. Since …