Bacterial communication (“quorum sensing”) via ligands and receptors: a novel pharmacologic target for the design of antibiotic drugs
…, NT Sucic, OD Terleckyj, JM Young - … of Pharmacology and …, 2005 - ASPET
The purpose of the present Perspectives is to present a synopsis of the literature on
bacterial “quorum sensing” as a background for the proposal that interference with this …
bacterial “quorum sensing” as a background for the proposal that interference with this …
The development of gestural communication in young chimpanzees
M Tomasello, BL George, AC Kruger, M Jeffrey… - Journal of Human …, 1985 - Elsevier
… Our final question concerned the process by which young chimpanzees come to acquire
these gestures. We had hoped to make observations relevant to this question for each gesture …
these gestures. We had hoped to make observations relevant to this question for each gesture …
Catecholaminergic polymorphic ventricular tachycardia in children: analysis of therapeutic strategies and outcomes from an international multicenter registry
…, ML Young, M Cabrera Ortega… - Circulation …, 2015 - Am Heart Assoc
Background— Catecholaminergic polymorphic ventricular tachycardia is an uncommon,
potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is …
potentially lethal, ion channelopathy. Standard therapies have high failure rates and little is …
[HTML][HTML] IL-13 is a driver of COVID-19 severity
Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection.
Understanding the mechanisms by which the immune system contributes to COVID-19 …
Understanding the mechanisms by which the immune system contributes to COVID-19 …
Evidence suggesting that the cardiomyocyte circadian clock modulates responsiveness of the heart to hypertrophic stimuli in mice
Circadian dyssynchrony of an organism (at the whole-body level) with its environment, either
through light-dark (LD) cycle or genetic manipulation of clock genes, augments various …
through light-dark (LD) cycle or genetic manipulation of clock genes, augments various …
The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: findings from an international multicentre registry
…, ML Young, SHJ Choi, M Cabrera Ortega… - Ep …, 2018 - academic.oup.com
Aims Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an ion channelopathy
characterized by ventricular arrhythmia during exertion or stress. Mutations in RYR2-…
characterized by ventricular arrhythmia during exertion or stress. Mutations in RYR2-…
[HTML][HTML] Therapeutic development of mesenchymal stem cells or their extracellular vesicles to inhibit autoimmune-mediated inflammatory processes in systemic lupus …
…, T Wada, H Steigelman, MC Young… - Frontiers in …, 2017 - frontiersin.org
Since being discovered over half a century ago, mesenchymal stem cells (MSCs) have been
investigated extensively to characterize their cellular and physiological influences. MSCs …
investigated extensively to characterize their cellular and physiological influences. MSCs …
Onset and distribution of tissue PrP accumulation in scrapie-affected Suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies
M Jeffrey, S Martin, JR Thomson, WS Dingwall… - Journal of Comparative …, 2001 - Elsevier
Tonsillar biopsies (single or multiple) or necropsies, or both, were performed on sheep
taken from a Suffolk flock in which frequent cases of scrapie had occurred over a period of …
taken from a Suffolk flock in which frequent cases of scrapie had occurred over a period of …
Dynamic stability of a human standing on a balance board
… In this work, we study the dynamic coupling between the neuromuscular system and a
balance board—an unstable platform often used to improve balance in young athletes, and older …
balance board—an unstable platform often used to improve balance in young athletes, and older …
Distribution and accumulation of PrP in gut-associated and peripheral lymphoid tissue of scrapie-affected Suffolk sheep
The distribution of disease-associated prion protein (PrP) was investigated in eight animals (20–24
months of age) from a flock of Suffolk sheep that had experienced frequent cases of …
months of age) from a flock of Suffolk sheep that had experienced frequent cases of …