User profiles for Jeffrey A. Silverman

Jeffrey Silverman

Jazz Pharmaceuticals
Verified email at jazzpharma.com
Cited by 5665

A 2.4% determination of the local value of the Hubble constant

…, MJ Reid, DO Jones, JM Silverman… - The Astrophysical …, 2016 - iopscience.iop.org
We use the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope (HST) to reduce
the uncertainty in the local value of the Hubble constant from 3.3% to 2.4%. The bulk of this …

SN 2006gy: discovery of the most luminous supernova ever recorded, powered by the death of an extremely massive star like η Carinae

…, AV Filippenko, JM Silverman… - The Astrophysical …, 2007 - iopscience.iop.org
We report the discovery and early observations of the peculiar Type IIn supernova (SN)
2006gy in NGC 1260. With a peak visual magnitude of about-22, it is the most luminous …

Berkeley Supernova Ia Program–I. Observations, data reduction and spectroscopic sample of 582 low-redshift Type Ia supernovae

JM Silverman, RJ Foley, AV Filippenko… - Monthly Notices of …, 2012 - academic.oup.com
In this first paper in a series, we present 1298 low-redshift (z ≲ 0.2) optical spectra of 582 Type
Ia supernovae (SNe Ia) observed from 1989 to 2008 as part of the Berkeley Supernova Ia …

Supernova SN 2011fe from an exploding carbon–oxygen white dwarf star

…, MT Kandrashoff, AV Filippenko, JM Silverman… - Nature, 2011 - nature.com
Type Ia supernovae have been used empirically as ‘standard candles’ to demonstrate the
acceleration of the expansion of the Universe 1 , 2 , 3 even though fundamental details, such …

Role of P‐glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

VJ Wacher, JA Silverman, Y Zhang… - Journal of …, 1998 - Wiley Online Library
Cytochrome P450 3A4 (CYP3A4), the major phase I drug metabolizing enzyme in humans,
and the MDR1 gene product P‐glycoprotein (P‐gp) are present at high concentrations in …

Inhibition of P-glycoprotein by D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)

JM Dintaman, JA Silverman - Pharmaceutical research, 1999 - Springer
Purpose. To investigate whether d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)
functions as an inhibitor of P-glycoprotein (P-gp), the multidrug resistance transporter. …

[HTML][HTML] Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine

JA Silverman, SR Deitcher - Cancer chemotherapy and pharmacology, 2013 - Springer
Vincristine (VCR) is a mainstay of treatment of hematologic malignancies and solid tumors
due to its well-defined mechanism of action, demonstrated anticancer activity and its ability to …

The lick AGN monitoring project: broad-line region radii and black hole masses from reverberation mapping of Hβ

…, Y Sakata, FJD Serduke, JM Silverman… - The Astrophysical …, 2009 - iopscience.iop.org
We have recently completed a 64-night spectroscopic monitoring campaign at the Lick
Observatory 3-m Shane telescope with the aim of measuring the masses of the black holes in 12 …

Type Iax supernovae: a new class of stellar explosion

…, G Pignata, MD Stritzinger, JM Silverman… - The Astrophysical …, 2013 - iopscience.iop.org
We describe observed properties of the Type Iax class of supernovae (SNe Iax), consisting
of SNe observationally similar to its prototypical member, SN 2002cx. The class currently has …

Swift J2058. 4+ 0516: discovery of a possible second relativistic tidal disruption flare?

…, F Olivares, P Schady, JM Silverman… - The Astrophysical …, 2012 - iopscience.iop.org
We report the discovery by the Swift hard X-ray monitor of the transient source Swift J2058. 4+
0516 (Sw J2058+ 05). Our multi-wavelength follow-up campaign uncovered a long-lived (…