Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats
…, S Chalon, J Hérault, D Guilloteau, JC Besnard… - The Journal of …, 1994 - Elsevier
This study examined the effects of dietary α-linolenic acid [18:3(n-3)] deficiency on dopaminergic
and serotoninergic neurotransmission systems in 60-d-old male rats. Rats were fed …
and serotoninergic neurotransmission systems in 60-d-old male rats. Rats were fed …
α‐Linolenic acid dietary deficiency alters age‐related changes of dopaminergic and serotoninergic neurotransmission in the rat frontal cortex
…, S Chalon, D Guilloteau, JC Besnard… - Journal of …, 1996 - Wiley Online Library
The effects of α‐linolenic acid diet deficiency on rat dopaminergic and serotoninergic
neurotransmission systems were investigated in the frontal cortex, striatum, and cerebellum of male …
neurotransmission systems were investigated in the frontal cortex, striatum, and cerebellum of male …
[HTML][HTML] Dietary fish oil affects monoaminergic neurotransmission and behavior in rats
…, D Guilloteau, AM Leguisquet, JC Besnard… - The Journal of …, 1998 - Elsevier
We studied the effects of a fish oil enriched diet on fatty acid composition of cerebral membranes
and on several neurochemical and behavioral variables of monoaminergic function in …
and on several neurochemical and behavioral variables of monoaminergic function in …
[HTML][HTML] Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n–3 polyunsaturated fatty acids
…, G Durand, D Guilloteau, S Bodard, JC Besnard… - Journal of lipid …, 2000 - ASBMB
We studied the effects of a diet chronically deficient in α-linolenic acid, the precursor of long-chain
n–3 polyunsaturated fatty acids, on dopaminergic neurotransmission in the shell …
n–3 polyunsaturated fatty acids, on dopaminergic neurotransmission in the shell …
Serotoninergic neurotransmission is affected by n‐3 polyunsaturated fatty acids in the rat
…, S Vancassel, D Guilloteau, JC Besnard… - Journal of …, 2004 - Wiley Online Library
We explored the effects of chronic α‐linolenic acid dietary deficiency on serotoninergic
neurotransmission. In vivo synaptic serotonin (5‐HT) levels were studied in basal and …
neurotransmission. In vivo synaptic serotonin (5‐HT) levels were studied in basal and …
Partial recovery of dopaminergic pathway after graft of adult mesenchymal stem cells in a rat model of Parkinson's disease
…, A Rico, D Guilloteau, P Charbord, JC Besnard… - Neurochemistry …, 2008 - Elsevier
Cellular therapy with adult stem cells appears as an opportunity for treatment of Parkinson's
disease. To validate this approach, we studied the effects of transplantation of rat adult bone-…
disease. To validate this approach, we studied the effects of transplantation of rat adult bone-…
Synthesis and Ligand Binding of Nortropane Derivatives: N-Substituted 2β-Carbomethoxy-3β-(4'-iodophenyl)nortropane and N-(3-Iodoprop-(2E)-enyl)-2β …
…, Y Frangin, L Mauclaire, JC Besnard… - Journal of medicinal …, 1997 - ACS Publications
Two novel series of iodinated N-substituted analogs of 2β-carbomethoxy-3β-(4‘-iodophenyl)tropane
(β-CIT) and N-(3-iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3‘,4‘-disubstituted …
(β-CIT) and N-(3-iodoprop-(2E)-enyl)-2β-carbomethoxy-3β-(3‘,4‘-disubstituted …
Age-related changes in phospholipid fatty acid composition and monoaminergic neurotransmission in the hippocampus of rats fed a balanced or an n-3 …
…, S Chalon, D Guilloteau, B Lejeune, JC Besnard… - Journal of lipid …, 1997 - ASBMB
The influence of aging (2, 6, 12, and 24 months) on hippocampal lipid composition and
neurochemical markers (endogenous noradrenaline, serotonin levels, monoamine oxidase (MOA…
neurochemical markers (endogenous noradrenaline, serotonin levels, monoamine oxidase (MOA…
Exploration of the dopamine transporter: in vitro and in vivo characterization of a high-affinity and high-specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl …
…, L Pourcelot, L Mauclaire, JC Besnard… - Nuclear medicine and …, 1998 - Elsevier
For the diagnosis and follow-up of neurodegenerative diseases, many cocaine derivatives
have been proposed as radioligands to explore the dopamine transporter. As none of them …
have been proposed as radioligands to explore the dopamine transporter. As none of them …
Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl) nortropane (LBT-999) as a highly promising fluorinated ligand for the …
…, S Bodard, Z Mincheva, JC Besnard… - … of Pharmacology and …, 2006 - ASPET
In the aim to develop an efficient fluorinated probe for positron emission tomography (PET)
exploration of the dopamine transporter (DAT), we studied several in vitro and in vivo …
exploration of the dopamine transporter (DAT), we studied several in vitro and in vivo …