Gene therapy progress and prospects: adenoviral vectors
JA St George - Gene therapy, 2003 - nature.com
In September 1999, the perceptions of the use of adenoviral (Ad) vectors for gene therapy
were altered when a patient exposed via the hepatic artery to a high dose of adenoviral vector …
were altered when a patient exposed via the hepatic artery to a high dose of adenoviral vector …
Adiabatic testing procedures for determining the self-heating propensity of coal and sample ageing effects
BB Beamish, MA Barakat, JD St George - Thermochimica acta, 2000 - Elsevier
An adiabatic testing procedure for determining the self-heating propensity of coal has been
evaluated using New Zealand coals. Repeatability of the self-heating rate (R 70 ), obtained …
evaluated using New Zealand coals. Repeatability of the self-heating rate (R 70 ), obtained …
Safety and efficacy of repetitive adenovirus–mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats
…, LA Couture, LD Keyes, MJ Lukason, JA St. George… - Nature …, 1994 - nature.com
Gene therapy for cystic fibrosis (CF) will require the safe transfer of CFTR cDNA to airway
epithelia in vivo. We showed previously that a recombinant adenovirus, Ad2/ CFTR–1, …
epithelia in vivo. We showed previously that a recombinant adenovirus, Ad2/ CFTR–1, …
Effect of the E4 region on the persistence of transgene expression from adenovirus vectors
…, CC Sookdeo, MP Smith, JA St George… - Journal of …, 1997 - Am Soc Microbiol
The utility of adenovirus vectors for gene therapy is limited by the transience of expression
that has been observed in various in vivo models. Immunological responses to viral targets …
that has been observed in various in vivo models. Immunological responses to viral targets …
Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications
…, SC Wadsworth, AE Smith, JA St. George… - Human gene …, 2001 - liebertpub.com
Cystic fibrosis (CF), an autosomal recessive disorder resulting from mutations in the cystic
fibrosis trans-membrane conductance regulator (CFTR) gene, is the most common lethal …
fibrosis trans-membrane conductance regulator (CFTR) gene, is the most common lethal …
Characterization of factors involved in modulating persistence of transgene expression from recombinant adenovirus in the mouse lung
…, KK Couture, SE Pennington, JA St. George… - Human gene …, 1997 - liebertpub.com
One potential limitation of adenovirus (Ad)-based vectors for the gene therapy of cystic fibrosis
(CF) and other genetic diseases is the transience of expression observed in most in vivo …
(CF) and other genetic diseases is the transience of expression observed in most in vivo …
A meta-regression of the long-term effects of deep brain stimulation on balance and gait in PD
… St. George has received postdoctoral fellowship support from the NIH (AG19706) and the
Parkinson's Alliance. Dr. Nutt has received funding for travel from Novartis and Teva …
Parkinson's Alliance. Dr. Nutt has received funding for travel from Novartis and Teva …
Fracture resistance of prepared teeth restored with bonded inlay restorations
AJ St-Georges, JR Sturdevant, EJ Swift Jr… - The Journal of prosthetic …, 2003 - Elsevier
STATEMENT OF PROBLEM: Tooth preparation weakens the remaining tooth structure.
PURPOSE: This study attempted to measure and compare the strength of intact, prepared, and …
PURPOSE: This study attempted to measure and compare the strength of intact, prepared, and …
[HTML][HTML] Trophic structure and a temporal shift in trophic diversity of mobile consumers in a subarctic estuary
Quantifying trophic relationships within and between species in terms of trophic position,
ontogeny and trophic diversity provides information on community-level structure and function. …
ontogeny and trophic diversity provides information on community-level structure and function. …
Programmed cell death in the germline
JS Baum, JPS George, K McCall - Seminars in Cell & Developmental …, 2005 - Elsevier
… Author links open overlay panel JS Baum , JP St. … KM and JB are supported by NIH grant
GM60574 and J.St.G. is supported by NSF DGE 0139325 and NIH grant ES07381 (to Ian …
GM60574 and J.St.G. is supported by NSF DGE 0139325 and NIH grant ES07381 (to Ian …