Pilocarpine administration has been used as an animal model for temporal lobe epilepsy since
it produces several morphological and synaptic features in common with human complex …

(1) Chemical destruction of the inferior olive (ION), or midline section interrupting the climbing
fibers (CFs) rapidly resulted in marked modifications of Purkinje cell (P. cell) simple spike (…

1. Fifty to ninety per cent of the Na efflux from axons of Loligo forbesi is inhibited by ouabain.
The properties of the ouabain‐sensitive component of the Na efflux are different from those …

Averaged cerebral potentials evoked by electrical stimulation of the fingers were investigated
in thirty-four full-term normal human newborns. The stimuli were delivered at intervals of at …

The present study was undertaken to gain insights into the mechanism of action of diazepam
in focally-evoked pilocarpine-induced seizures by concomitantly assessing the changes …

Limbic seizures were evoked in freely moving rats by intrahippocampal administration of the
muscarinic agonist pilocarpine viathe microdialysis probe (10 mM for 40 min at 2 μl/min). …

Arylsulfatase A (ASA)-deficient (−/−) mice and ASA(+/+) controls were constructed as a
transgenic model for the lysosomal storage disease, metachromatic leukodystrophy (MLD). One-…

Levels of methylguanidine (MG) and guanidinosuccinate (GSA) are known to be highly
increased in uraemic patients. In the present work, the effects of these uraemic guanidino …

Cortical somatosensory evoked potentials were used to measure secondary hyperaesthesia
resulting from subcutaneous 1 and 5% formalin in unanesthetized rats with permanently …

As yet, the in vivo epileptogenic properties of guanidinosuccinic acid (GSA) remained highly
conjectural, still requiring the demonstration of GSA-induced behavioral convulsions …