User profiles for J. D. Schmitt
Joseph D SchmittResearch Fishery Biologist, USGS Great Lakes Science Center, Lake Erie Biological Station Verified email at usgs.gov Cited by 340 |
Exploring the nature of molecular recognition in nicotinic acetylcholine receptors
JD Schmitt - Current medicinal chemistry, 2000 - ingentaconnect.com
… Also, Schmitt and coworkers [130] have established that the cationic moieties of various
nAChR ligands interact with aromatic groups to an extent proportional to their equilibrium …
nAChR ligands interact with aromatic groups to an extent proportional to their equilibrium …
[HTML][HTML] Propranolol, a phosphatidate phosphohydrolase inhibitor, also inhibits protein kinase C.
…, CE McCall, JT O'flaherty, JD Schmitt, JD Kent… - Journal of Biological …, 1992 - Elsevier
Propranolol, a beta-adrenergic receptor antagonist, also inhibits phosphatidate phosphohydrolase,
the enzyme that converts phosphatidic acid into diacylglycerol. This latter effect has …
the enzyme that converts phosphatidic acid into diacylglycerol. This latter effect has …
Feeding ecology of generalist consumers: a case study of invasive blue catfish Ictalurus furcatus in Chesapeake Bay, Virginia, USA
Globally, invasive species cause extensive economic damage and are a major threat to
biodiversity. Generalist species are particularly dangerous invaders, as they can thrive in …
biodiversity. Generalist species are particularly dangerous invaders, as they can thrive in …
Effectiveness of DNA barcoding for identifying piscine prey items in stomach contents of piscivorous catfishes
Introduced predators pose ecological impacts upon prey species and receiving ecosystems.
Understanding such ecological interactions creates technical challenges including species-…
Understanding such ecological interactions creates technical challenges including species-…
Predation and prey selectivity by nonnative catfish on migrating alosines in an Atlantic slope estuary
Native to the central USA, the Blue Catfish Ictalurus furcatus and the Flathead Catfish Pylodictis
olivaris have been widely introduced into many Atlantic slope rivers and are now found …
olivaris have been widely introduced into many Atlantic slope rivers and are now found …
Targeting neuronal nicotinic receptors: a path to new therapies
M Bencherif, JD Schmitt - Current Drug Targets-CNS & …, 2002 - ingentaconnect.com
The structural heterogeneity, the ubiquity of anatomical distribution, and the demonstrated
modulation of biological functions is consistent with the view that nicotinic cholinergic …
modulation of biological functions is consistent with the view that nicotinic cholinergic …
Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols
LW Daniel, GW Small, JD Schmitt, CJ Marasco… - Biochemical and …, 1988 - Elsevier
Alkylacylglycerols are synthesized when choline-phospholipids are degraded by a phospholipase
C. This class of compounds has been shown to have biological activities; however, …
C. This class of compounds has been shown to have biological activities; however, …
Molecular recognition in nicotinic acetylcholine receptors: The importance of π− cation interactions
JD Schmitt, CGV Sharples… - Journal of medicinal …, 1999 - ACS Publications
We explore the significance of π−cation interactions in the binding of ligands to nicotinic
acetylcholine receptors. Specifically, the Austin method of semiempirical molecular orbital …
acetylcholine receptors. Specifically, the Austin method of semiempirical molecular orbital …
2-(Arylmethyl)-3-substituted quinuclidines as selective α7 nicotinic receptor ligands
…, L Miao, TY Phillips, A Seamans, JD Schmitt… - Bioorganic & Medicinal …, 2005 - Elsevier
A series of 2-(arylmethyl)-3-substituted quinuclidines was developed as α7 neuronal nicotinic
acetylcholine receptor (nAChR) agonists based on a putative pharmacophore model. The …
acetylcholine receptor (nAChR) agonists based on a putative pharmacophore model. The …
AhpF can be dissected into two functional units: tandem repeats of two thioredoxin-like folds in the N-terminus mediate electron transfer from the thioredoxin reductase …
LB Poole, A Godzik, A Nayeem, JD Schmitt - Biochemistry, 2000 - ACS Publications
AhpF, the flavin-containing component of the Salmonella typhimurium alkyl hydroperoxide
reductase system, catalyzes the NADH-dependent reduction of an active-site disulfide bond …
reductase system, catalyzes the NADH-dependent reduction of an active-site disulfide bond …