CGS 9343B, a novel, potent, and selective inhibitor of calmodulin activity.
…, J Ansell, GA Stone, LP Wennogle, JW Wasley - Molecular …, 1987 - ASPET
1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]- benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-o
ne (1:1) maleate was synthesized in six steps from methyl …
ne (1:1) maleate was synthesized in six steps from methyl …
A novel calmodulin antagonist, CGS 9343B, modulates calcium-dependent changes in neurite outgrowth and growth cone movements
KA Polak, AM Edelman, JW Wasley… - Journal of …, 1991 - Soc Neuroscience
The neurotransmitter 5-HT alters growth cone motility and neurite elongation in neuron B19,
isolated from the buccal ganglion of Helisoma trivolvis (Haydon et al., 1984). The effects of 5-…
isolated from the buccal ganglion of Helisoma trivolvis (Haydon et al., 1984). The effects of 5-…
CGS 20625, a novel pyrazolopyridine anxiolytic.
…, M Schmutz, N Yokoyoma, JW Wasley - … of Pharmacology and …, 1989 - ASPET
CGS 20625 (2-(4-methoxyphenyl)2,3,5,6,7,8,9,10-octa hydrocyclohepta[b]pyrazolo-[3,4-d]pyridin-3-one)
is a potent and selective ligand for the central benzodiazepine receptor (IC50 = …
is a potent and selective ligand for the central benzodiazepine receptor (IC50 = …
[PDF][PDF] Novel calmodulin antagonist CGS 9343B inhibits secretory diarrhea.
JE Shook, TF Burks, JW Wasley, JA Norman - Journal of Pharmacology …, 1989 - Citeseer
The goal of this study was to determine whether secretory diarrhea could be ameliorated by
pharmacological alteration of the second messenger systems which mediate intestinal fluid …
pharmacological alteration of the second messenger systems which mediate intestinal fluid …
Characterization of CGS 8515 as a selective 5-lipoxygenase (5-LO) inhibitor.
…, D White, TD Oglesby, JW Wasley - Advances in …, 1989 - europepmc.org
1. CGS 8515 selectively inhibited 5-LO (IC50= 0.1 microM) with negligible effect on CO, 12-LO,
15-LO and TxS at concentrations up to 100 microM. 2. CGS 8515 selectively inhibited …
15-LO and TxS at concentrations up to 100 microM. 2. CGS 8515 selectively inhibited …
[CITATION][C] CGS 20625, a novel pyrazolopyridine with selective anxiolytic activity.
…, M Schmutz, N Yokoyoma, JW Wasley… - Progress in Clinical …, 1990 - europepmc.org
CGS 20625, a novel pyrazolopyridine with selective anxiolytic activity. - Abstract - Europe PMC
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Sign in | Create an account https://orcid.org Europe PMC Menu About Tools Developers Help …
Recommendations for identification and public health management of persons with chronic hepatitis B virus infection
…, SA Wang, L Finelli, A Wasley, SM Neitzel, JW Ward - 2008 - stacks.cdc.gov
Serologic testing for hepatitis B surface antigen (HBsAg) is the primary way to identify persons
with chronic hepatitis B virus (HBV) infection. Testing has been recommended previously …
with chronic hepatitis B virus (HBV) infection. Testing has been recommended previously …
CMorophyllides c
JWF Wasley, WT Scott, AS Holt - Canadian Journal of …, 1970 - cdnsciencepub.com
"Chlorophyllides" c were obtained from methanol–tetrahydrofuran extracts of
Phaeodactylum tricornutum by retention on an anion exchange resin. They were esterified (diazomethane) …
Phaeodactylum tricornutum by retention on an anion exchange resin. They were esterified (diazomethane) …
SHP-2 and PD-L1 inhibition combined with radiotherapy enhances systemic antitumor effects in an anti–PD-1–resistant model of non–small cell lung cancer
Immune checkpoint inhibitors, such as anti–PD-1/PD-L1, have emerged as promising
therapies for advanced non–small cell lung cancer (NSCLC). However, approximately 80% of …
therapies for advanced non–small cell lung cancer (NSCLC). However, approximately 80% of …
Senolytic cocktail dasatinib plus quercetin enhances the antitumor effect of senescence-inducing radiotherapy in a preclinical model of melanoma
Purpose/Objective(s) Although radiation is beneficial in killing tumor cells, it also causes
accumulation of senescent cells in tumors and in the surrounding healthy tissue. Senescent …
accumulation of senescent cells in tumors and in the surrounding healthy tissue. Senescent …