Ibogaine is a naturally occurring compound with purported antiaddictive properties. When
administered to primates, ibogaine is rapidlyo-demethylated to form the metabolite 12-…

The putative anti-addiction alkaloid ibogaine and its principal metabolite 12-hydroxyibogamine
appear to act at the (+)-5 methyl-10,11-dihydro-5H-dibenzo[a,d]cycloheten-5–10-imine …

Ibogaine (IBO) is a plant‐derived alkaloid that is being evaluated as a possible medication
for substance use disorders. When administered peripherally to monkeys and humans, IBO is …

NORIBOGAINE is formed in vivo by the O-demethylation of the indole alkaloid ibogaine. We
report here that noribogaine acts as a full agonist at the μ-opioid receptor. Noribogaine-…

On 10 October 2011, a submarine volcanic eruption started 2 km south from El Hierro Island
(Spain). Since July 2011 a dense multiparametric monitoring network was deployed all over …

The last two decades have witnessed a dramatic growth of wearable sensor technology,
mainly represented by flexible, stretchable, on‐skin electronic sensors that provide rich …

Drilling an ultra-deep hole in an intact portion of oceanic lithosphere, through the crust to
the Mohorovičić discontinuity (the ‘Moho’), and into the uppermost mantle is a long-standing …

… Martín de Pablos JL … Márquez Contreras E, Gil Guillén V, Casado Martínez JJ, Martel
Claros N, De la Figuera von Wichmann M, Martín de Pablos JL, Atienza Martín F, Gros García …

… Teas from Japan are located at the left side of the plot, at negative values of PC1. Most of
the Chinese teas are situated at positive values of PC1, except samples 7Chg and 2Chg that …

New experimental approaches are required to detect the elusive transient intermediates
predicted by simulations of virus assembly or disassembly. Here, an atomic force microscope (…