A novel mechanism of activity‐dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.

JN Kew, G Trube, JA Kemp - The Journal of physiology, 1996 - Wiley Online Library
1. Ifenprodil is a selective, atypical non‐competitive antagonist of NMDA receptors that contain
the NR2B subunit with an undefined mechanism of action. Ifenprodil is neuroprotective in …

Arsenic and mercury intoxication due to Indian ethnic remedies.

J Kew, C Morris, A Aihie, R Fysh, S Jones… - BMJ: British Medical …, 1993 - ncbi.nlm.nih.gov
We have recently seen two cases of heavy metal intoxication resulting from ingestion of
Indian ethnic remedies. The substances were dispensed by an Indian ethnic practitioner, or …

Abnormal access of axial vibrotactile input to deafferented somatosensory cortex in human upper limb amputees

JJM Kew, PW Halligan, JC Marshall… - Journal of …, 1997 - journals.physiology.org
John JM KewJohn JM Kew … et al. 1994), and that similar increased excitability of the
deafferented S1 and PPC may be important in the genesis of phantom limb perceptions (Kew et al. …

Investigation of the H+myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling

ED Daniel, JN Kew, PR Maycox - Biochemical Society …, 2009 - portlandpress.com
Phosphoinositide signalling regulates a series of important neuronal processes that are
thought to be altered in mood disorders. Furthermore, mood-stabilizing drugs inhibit key …

[BOOK][B] Business environment: managing in a strategic context

J Kew, J Stredwick - 2008 - books.google.com
… The right of John Kew and John Stredwick to be identified as authors of this work has
been asserted by them in accordance with sections 77 and 78 of the Copyright, Designs and …

Death of developing septal cholinergic neurons following NGF withdrawal in vitro: protection by protein synthesis inhibition

CN Svendsen, JN Kew, K Staley… - Journal of …, 1994 - Soc Neuroscience
Fetal septal neurons were grown in vitro under glass coverslips. This sandwich culture
method significantly increased general neuronal survival, reduced glial proliferation, and …

Long‐term transgene expression can be mediated in the brain by adenoviral vectors when powerful neuron‐specific promoters are used

…, M Hopton, TC Harding, JN Kew… - The Journal of Gene …, 2003 - Wiley Online Library
Background Adenoviral (Ad) vectors are one of the most widely used tools for modelling gene
therapy strategies. However, they have not been used in long‐term models of neurological …

[HTML][HTML] Dysregulation of specialized delay/interference-dependent working memory following loss of dysbindin-1A in schizophrenia-related phenotypes

…, EM Shapland, DC Henshall, JN Kew… - …, 2017 - nature.com
Dysbindin-1, a protein that regulates aspects of early and late brain development, has been
implicated in the pathobiology of schizophrenia. As the functional roles of the three major …

Transfection with hsp70i protects rat dorsal root ganglia neurones and glia from heat stress.

JB Uney, K Staley, P Tyers, MV Sofroniew, JN Kew - Gene Therapy, 1994 - europepmc.org
Studies have shown that the induction of heat shock proteins (hsp's) in the CNS is protective
against excitotoxicity and correlative evidence also suggest that hsp's may be protective …

Civil society and peace negotiations: Confronting exclusion

D Kew, AWS John - International Negotiation, 2008 - brill.com
The fact that civil society groups play important roles in post-conflict peacebuilding has
entered the mainstream of international conflict resolution dogma. Rarely do local civil society …