Statistical significance testing is the cornerstone of quantitative research, but studies that fail
to report measures of effect size are potentially missing a robust part of the analysis. We …

… JM Maher is a Japan Society for the Promotion of Science postdoctoral fellow. Address
reprint requests to: Curtis Klaassen, Ph.D., Department of Pharmacology, Toxicology, and …

The multidrug resistance-associated proteins (Mrp) are ATP-dependent transporters that
export a variety of conjugated and unconjugated compounds out of cells. There are nine …

… JaneMaree Maher was responsible for the first interpretation of the transcripts of the
women … JaneMaree Maher saw that women’s refusal to view their mothering as all-encompassing …

Keap1 regulates Nrf2 activity in response to xenobiotic and oxidative stresses. Nrf2 is an
essential regulator of cytoprotective genes. Keap1-null mice are lethal by weaning age due to …

Breast cancer resistance protein (Bcrp/Abcg2) is a member of the ABC transporter family.
The purpose of this study was to quantify Bcrp mRNA in rat and mouse tissues, and to …

The Nrf2 transcription factor is crucial for regulating the cellular defense against various
carcinogens. However, relationship between host Nrf2 and cancer metastasis remains …

NF-E2-related factor 2 (Nrf2) regulates antioxidant-responsive element-mediated induction
of cytoprotective genes in response to oxidative stress. The purpose of this study was to …

Analysis of the mouse genome has revealed eight multidrug resistance-associated (Mrp)
transporters, with mouse homologs for all human MRPs except MRP8. Whereas MRP …

Currently in developed nations, childhood obesity is generating widespread concern and
prompting social and institutional responses. Obesity is constructed as a broad public health …