Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution
JP Wery, RW Schevitz, DK Clawson, JL Bobbitt… - Nature, 1991 - nature.com
LETTERS TO NATURE Page 1 LETTERS TO NATURE Enlargement of the CAG repeat thus
appears to be specific to X-linked SBMA. We propose that the corresponding increase in the …
appears to be specific to X-linked SBMA. We propose that the corresponding increase in the …
Crystalline l-asparaginase from Escherichia coli B: I. purification and chemical characterization
PPK Ho, EB Milikin, JL Bobbitt, EL Grinnan… - Journal of Biological …, 1970 - ASBMB
Purification of l-asparaginase from Escherichia coli B is described. The enzyme is crystallized
from a partially purified preparation in the presence of cations and aqueous alcohol. …
from a partially purified preparation in the presence of cations and aqueous alcohol. …
Interleukin 1-induced pathophysiology: induction of cytokines, development of histopathologic changes, and immunopharmacologic intervention
…, RL Cain, PE Riedl, KM Mohler, JL Bobbitt… - Clinical immunology and …, 1989 - Elsevier
In this report, we describe a murine system in which treatment with recombinant human
interleukin 1 (IL-1) induced an acute lethal state with pathologic changes similar to septic shock …
interleukin 1 (IL-1) induced an acute lethal state with pathologic changes similar to septic shock …
Calcitonin stimulates plasminogen activator in porcine renal tubular cells: LLC-PK1.
JM Dayer, JD Vassalli, JL Bobbitt, RN Hull… - The Journal of cell …, 1981 - rupress.org
Plasminogen activators are highly selective proteases that activate the proenzyme
plasminogen to the general protease, plasmin. We studied a porcine kidney cell line, originally …
plasminogen to the general protease, plasmin. We studied a porcine kidney cell line, originally …
Transgenic model for the discovery of novel human secretory non-pancreatic phospholipase A2 inhibitors
…, NJ Bach, RD Dillard, SE Draheim, JL Bobbitt… - European journal of …, 1996 - Elsevier
… Lawton and JL Browning, 1991, Human extracellular recombinant phospholipase A 2 …
Snyder, DW, CD Sommers, JL Bobbitt and ED Mihelich, 1993, Characterization of the contractile …
Snyder, DW, CD Sommers, JL Bobbitt and ED Mihelich, 1993, Characterization of the contractile …
Porcine pancreatic phospholipase A2-induced contractions of guinea pig lung pleural strips
CD Sommers, JL Bobbitt, KG Bemis… - European journal of …, 1992 - Elsevier
The contractile nature of porcine pancreatic phospholipase A 2 (PLA 2 ) was characterized
on paired pleural strips obtained from guinea pig lung. PLA 2 (0.003–10 U/ml) produced …
on paired pleural strips obtained from guinea pig lung. PLA 2 (0.003–10 U/ml) produced …
Thrombolytic activity of a novel plasminogen activator, LY210825, compared with recombinant tissue-type plasminogen activator in a canine model of coronary artery …
…, TJ Craft, JL Sundboom, BW Grinnell, JL Bobbitt… - Circulation, 1990 - Am Heart Assoc
LY210825, a recombinant tissue-type plasminogen activator (rt-PA), which contains the
kringle-2 and serine protease functional domains of native tissue-type plasminogen activator, …
kringle-2 and serine protease functional domains of native tissue-type plasminogen activator, …
Use of peptidyl-4-methoxy-2-naphthylamides to assay plasmin
SA Clavin, JL Bobbitt, RT Shuman… - Analytical …, 1977 - Elsevier
Several tripeptide amides of 4-methoxy-2-naphthylamide were synthesized and tested as
possible substrates for human plasmin. These peptides contained arginine or lysine as the …
possible substrates for human plasmin. These peptides contained arginine or lysine as the …
Recombinant human secretory phospholipase A2 released thromboxane from guinea pig bronchoalveolar lavage cells: in vitro and ex vivo evaluation of a novel …
…, SM Spaethe, WT Jackson, JL Bobbitt… - … of Pharmacology and …, 1996 - ASPET
The primary objective of this study was to develop a functional assay that could provide
rapid and reliable information on some pharmacologic characteristics of a novel inhibitor of …
rapid and reliable information on some pharmacologic characteristics of a novel inhibitor of …
Immunocytochemical localization of plasminogen activator on porcine kidney cell strain: LLC-PK1 (LP100).
DC Paul, JL Bobbitt, DC Williams… - … of Histochemistry & …, 1979 - journals.sagepub.com
An antibody to plasminogen activator (PA) produced by the cultured cells of the pig kidney
cell strain LLC-PK1 (LP100) was used to localize PA on the cell's free (unattached) surface. …
cell strain LLC-PK1 (LP100) was used to localize PA on the cell's free (unattached) surface. …