Role of intracellular calcium signaling in the pathophysiology and pharmacotherapy of bipolar disorder: current status

JJ Warsh, S Andreopoulos, PP Li - Clinical Neuroscience Research, 2004 - Elsevier
Evidence implicating disturbances of intracellular Ca 2+ homeostasis has continued to
accumulate, with a recent burst of new observations obtained using cultured cell lines from …

Elevated serotonin transporter binding in depressed patients with Parkinson's disease: A preliminary PET study with [11C]DASB

I Boileau, JJ Warsh, M Guttman… - … : official journal of the …, 2008 - Wiley Online Library
This study investigated whether abnormalities in serotonin transporter binding occur in
Parkinson's disease (PD) patients with concurrent depression. We estimated serotonin …

Decreased cerebral cortical serotonin transporter binding in ecstasy users: a positron emission tomography/[11C]DASB and structural brain imaging study

…, M Guttman, DL Collins, C Shapiro, JJ Warsh… - Brain, 2010 - academic.oup.com
Animal data indicate that the recreational drug ecstasy (3,4-methylenedioxymethamphetamine)
can damage brain serotonin neurons. However, human neuroimaging measurements of …

Effect of oxidative stress on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder

…, W Au‐Yeung, T Scarcelli, PP Li, JJ Warsh - Bipolar …, 2012 - Wiley Online Library
Roedding AS, Gao AF, Au‐Yeung W, Scarcelli T, Li PP, Warsh JJ. Effect of oxidative stress
on TRPM2 and TRPC3 channels in B lymphoblast cells in bipolar disorder. Bipolar Disord …

Reduced brain 5-HT and elevated NE turnover and metabolites in bipolar affective disorder

LT Young, JJ Warsh, SJ Kish, K Shannak… - Biological …, 1994 - Elsevier
Levels of norepinephrine (NE), serotonin (5-HT), dopamine (DA), and their major metabolites
were determined in postmortem brain obtained from nine subjects with antemortem …

Increased phospholipid breakdown in schizophrenia: evidence for the involvement of a calcium-independent phospholipase A2

BM Ross, C Hudson, J Erlich, JJ Warsh… - Archives of general …, 1997 - jamanetwork.com
Background: Magnetic resonance spectroscopy studies have suggested above-normal
turnover of membrane phospholipids in brains of patients with schizophrenia. One possible …

CNS signal transduction in the pathophysiology and pharmacotherapy of affective disorders and schizophrenia

CJ Hudson, LT Young, PP Li, JJ Warsh - Synapse, 1993 - Wiley Online Library
Until recently, research on the neurochemical basis of affective disorders (AD) and schizophrenia
(SCZ) focused on detecting postulated disturbances in presynaptic neurotransmitter …

[PDF][PDF] High intracellular calcium concentrations in transformed lymphoblasts from subjects with bipolar I disorder

…, S Parikh, J Sen, A Kamble, JJ Warsh - American Journal of …, 1997 - researchgate.net
… Hudson CJ, Young LT, Li PP, Warsh JJ: CNS signal transduction in the pathophysiology
and … Warsh JJ, Li PP: Second messenger systems and mood disorders. Current Opinion in …

Cytoprotection by lithium and valproate varies between cell types and cellular stresses

JS Lai, C Zhao, JJ Warsh, PP Li - European journal of pharmacology, 2006 - Elsevier
Despite much evidence that lithium and valproate, two commonly used mood stabilizers,
exhibit neuroprotective properties against an array of insults, the pharmacological relevance of …

Differential alteration of phospholipase A2 activities in brain of patients with schizophrenia

BM Ross, S Turenne, A Moszczynska, JJ Warsh… - Brain research, 1999 - Elsevier
We recently reported that the activity of a calcium-independent subtype of phospholipase A
2 is increased in blood of patients with schizophrenia. The present investigation examined …