This paper reviews the recent data on the role of vitamin D (VD) in the genesis of various
immunological disorders. It inhibits immune reactions in general, but it enhances the …

Our recent study [1] on synthetic analogs of enkephalins (Tyr-Gly-Gly-Phe-X, X= Met and Leu
[2]) has revealed some structural requirements for a pentapeptide to exert antinociceptive …

HUGHES et al. have reported the isolation and structure of two pentapeptides from porcine
brain with opiate agonist activity in isolated systems. The structure of one of these peptides, …

Repeated administration of morphine resulted in significant reduction of its analgesic potency.
If 0.1 mg/kg α-MSH was coadministered, the tolerance development was attenuated, 1 mg/…

The recent literature on the antinociceptive action of ionotropic glutamate receptor antagonists
is reviewed with special emphasis on their clinical potential. Actually the glutamatergic …

In the present study, the pharmacological effects of etiprednol dicloacetate (BNP-166; ethyl-17α-dichloroacetoxy-11β-hydroxyandrosta-1,4-diene-3-one-17β-carboxylate),
a new soft …

The effects of [D-Met 2 ,Pro 5 ]enkephalinamide, morphine and naloxone have been examined
in two different models of experimentally elicited gastric mucosal lesions. One of them …

The behavioral effects of dextromethorphan (DM), dextrorphan (DO) and phencyclidine (PCP)
were compared in rats. DO (15–120 mg/kg) was similar to PCP (1.25–20 mg/kg) in …

Met-enkephalin and its Pro 5 analogs containing Gly or D amino acids at position 2 were
subjected to digestion with aminopeptidase M, rat brain extracts and human sera. The enzyme …

Experiments were performed to establish the development of cross tolerance between
morphine and the C-terminal fragment of porcine β-lipotropin /LPH 61–91 , β-endorphin/ in rats. …