The 1000 Genomes Project set out to provide a comprehensive description of common human
genetic variation by applying whole-genome sequencing to a diverse set of individuals …

Background Whole-exome sequencing is a diagnostic approach for the identification of
molecular defects in patients with suspected genetic disorders. Methods We developed technical…

Autism spectrum disorders (ASD) are believed to have genetic and environmental origins,
yet in only a modest fraction of individuals can specific causes be identified 1 , 2 . To identify …

A major challenge of biology is understanding the relationship between molecular genetic
variation and variation in quantitative traits, including fitness. This relationship determines our …

A major goal in human genetics is to use natural variation to understand the phenotypic
consequences of altering each protein-coding gene in the genome. Here we used exome …

Measurements of charged pion and kaon production in central Pb+ Pb collisions at 40, 80,
and 158 A GeV are presented. These are compared with data at lower and higher energies …

We report here genome sequences and comparative analyses of three closely related
parasitoid wasps: Nasonia vitripennis, N. giraulti, and N. longicornis. Parasitoids are important …

Many genomes have been sequenced to high-quality draft status using Sanger capillary
electrophoresis and/or newer short-read sequence data and whole genome assembly …

The NA49 detector is a wide acceptance spectrometer for the study of hadron production in
p+p, p+A, and A+A collisions at the CERN SPS. The main components are 4 large-volume …

Background Whole-genome sequencing may revolutionize medical diagnostics through rapid
identification of alleles that cause disease. However, even in cases with simple patterns of …