Pluripotency pertains to the cells of early embryos that can generate all of the tissues in the
organism. Embryonic stem cells are embryo-derived cell lines that retain pluripotency and …

Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular
zone and outer subventricular zone. Although outer subventricular zone radial glia may …

Systematic analyses of spatiotemporal gene expression trajectories during organogenesis
have been challenging because diverse cell types at different stages of maturation and …

Mechanistic roles for many lncRNAs are poorly understood, in part because their direct
interactions with genomic loci and proteins are difficult to assess. Using a method to purify …

Photonic bandgap structures use the principle of interference to reflect radiation. Reflection
from photonic bandgap structures has been demonstrated in one, two and three dimensions …

We have developed a methodology we call ROMA (representational oligonucleotide microarray
analysis), for the detection of the genomic aberrations in cancer and normal humans. By …

The rarity and inaccessibility of the earliest primordial germ cells (PGCs) in the mouse
embryo thwart efforts to investigate molecular mechanisms of germ-cell specification. stella (also …

Long noncoding RNAs (lncRNAs) have important regulatory roles and can function at the
level of chromatin. To determine where lncRNAs bind to chromatin, we developed capture …

Direct comparisons of human and non-human primate brains can reveal molecular pathways
underlying remarkable specializations of the human brain. However, chimpanzee tissue is …

The role of C17:0 and C15:0 in human health has recently been reinforced following a number
of important biological and nutritional observations. Historically, odd chain saturated fatty …