User profiles for J R Mitchell
James MitchellAssociate Professor of Genetics and Complex Diseases, Harvard TH Chan School of Public … Verified email at hsph.harvard.edu Cited by 14838 |
Telomerase in the human organism
K Collins, JR Mitchell - Oncogene, 2002 - nature.com
… of full-length TERT, suggesting that DKC cancers do not necessarily require an ALT
pathway for telomere maintenance (JR Mitchell, J Wong and K Collins, unpublished data). …
pathway for telomere maintenance (JR Mitchell, J Wong and K Collins, unpublished data). …
Interventions to slow aging in humans: are we ready?
…, F Madeo, MG Mirisola, JR Mitchell… - Aging cell, 2015 - Wiley Online Library
The workshop entitled ‘Interventions to Slow Aging in Humans: Are We Ready?’ was held in
Erice, Italy, on October 8–13, 2013, to bring together leading experts in the biology and …
Erice, Italy, on October 8–13, 2013, to bring together leading experts in the biology and …
Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis
JR MITCHELL, HJ ZIMMERMAN, KG ISHAK… - Annals of internal …, 1976 - acpjournals.org
The clinical spectrum of isoniazid-induced liver injury seems to be clinically, biochemically,
and histologically indistinguishable from viral hepatitis, except that the injury occurs primarily …
and histologically indistinguishable from viral hepatitis, except that the injury occurs primarily …
Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic metabolite
DJ Jollow, JR Mitchell, N Zampaglione, JR Gillette - Pharmacology, 1974 - karger.com
This laboratory has previously postulated that bromobenzene-induced hepatic necrosis
results from the formation of a reactive metabolite that arylates vital cellular macromolecules. …
results from the formation of a reactive metabolite that arylates vital cellular macromolecules. …
Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione
JR Mitchell, DJ Jollow, WZ Potter, JR Gillette… - … of Pharmacology and …, 1973 - ASPET
The possibility that glutathione may protect against acetaminophen-induced hepatic
necrosis was examined. Pretreatment of mice with diethyl maleate, which depletes hepatic …
necrosis was examined. Pretreatment of mice with diethyl maleate, which depletes hepatic …
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism
JR Mitchell, DJ Jollow, WZ Potter, DC Davis… - … of Pharmacology and …, 1973 - ASPET
A number of recent reports indicate that massive overdoses of acetaminophen can produce
a fulminant hepatic necrosis in man. Acetaminophen-induced hepatic necrosis thereforne …
a fulminant hepatic necrosis in man. Acetaminophen-induced hepatic necrosis thereforne …
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo
…, JR Mitchell, WZ Potter, DC Davis, JR Gillette… - … of Pharmacology and …, 1973 - ASPET
Doses of 3 H-acetaminophen (300-750 mg/kg) that cause necrosis in mice were shown to
result in large amounts of radiolabeled material covalently bound to mouse liver protein in vivo …
result in large amounts of radiolabeled material covalently bound to mouse liver protein in vivo …
Giant magnetoresistance in heterogeneous Cu-Co alloys
AE Berkowitz, JR Mitchell, MJ Carey, AP Young… - Physical Review Letters, 1992 - APS
We have observed giant magnetoresistance in heterogeneous thin film Cu-Co alloys
consisting of ultrafine Co-rich precipitate particles in a Cu-rich matrix. The magnetoresistance …
consisting of ultrafine Co-rich precipitate particles in a Cu-rich matrix. The magnetoresistance …
[PDF][PDF] An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA
…, SA Youssef, F Rodier, W Toussaint, JR Mitchell… - Developmental cell, 2014 - cell.com
Cellular senescence suppresses cancer by halting the growth of premalignant cells, yet the
accumulation of senescent cells is thought to drive age-related pathology through a …
accumulation of senescent cells is thought to drive age-related pathology through a …
Relative contributions of history-taking, physical examination, and laboratory investigation to diagnosis and management of medical outpatients.
JR Hampton, MJ Harrison, JR Mitchell, JS Prichard… - Br Med J, 1975 - bmj.com
To evaluate the relative importance of the medical history, the physical examination, and
laboratory investigations in the diagnosis and management of medical outpatients some …
laboratory investigations in the diagnosis and management of medical outpatients some …