The gradual recovery of activity of serotonergic neurons following an initial inhibition has
been hypothesized to play an important role in the delayed onset of efficacy of selective …

LY426965 [(2S)-(+)-1-cyclohexyl-4-[4-(2-methoxyphenyl)-1-piperazinyl]2-methyl-2-phenyl-1-butanone
monohydrochloride] is a novel compound with high affinity for the cloned human 5…

Acute and chronic administration of low doses (eg 0.1, 0.3 mg/kg ip) of the selective 5-HT 3
antagonist zatosetron decreased the number of spontaneously active A 10 dopamine cells …

In order to explore the neurophysiology of nicotine withdrawal, we examined the activity of
serotonergic neurons in the dorsal raphe nucleus in rats undergoing withdrawal from chronic …

Electrophysiological Effects of Diphenylpyrazolidinone Cholecystokinin-B and
Cholecystokinin-A Antagonists on Midbrain Dopamine Page 1 VoL 264, No. 1 Printed in …

In order to explore the neurophysiology of nicotine withdrawal, we examined the activity of
substantia nigra (A9) and ventral tegmental area (A10) dopamine cells in rats undergoing …

The activity of LY288513, an investigational cholecystokinin (CCK) B antagonist, was evaluated
in a wide range of pharmacological tests in mice and rats. The anxiolytic benzodiazepine…

Chronic administration of antipsychotic drugs has previously been shown to decrease the
number of spontaneously active midbrain dopamine cells. In an effort to evaluate CCK …

IN order to explore the potential clinical utility of CCK-B antagonists for the treatment of
nicotine withdrawal symptoms, the auditory startle reflex was examined in rats undergoing …

Pre-pulse inhibition (PPI) of the acoustic startle response is the diminution of the startle
response when the startle stimulus is preceded by a weaker, non-startle-eliciting stimulus. …