Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase

JB Cheng, MA Levine, NH Bell… - Proceedings of the …, 2004 - National Acad Sciences
The synthesis of bioactive vitamin D requires hydroxylation at the 1α and 25 positions by
cytochrome P450 enzymes in the kidney and liver, respectively. The mitochondrial enzyme …

RANSAC-based DARCES: A new approach to fast automatic registration of partially overlapping range images

CS Chen, YP Hung, JB Cheng - IEEE Transactions on Pattern …, 1999 - ieeexplore.ieee.org
… We would also like to thank Allen Hanson, and Yong-Qing Cheng for their constructive
comments and suggcstions. This material is based an work supported in part by the US National …

[HTML][HTML] De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxylase

JB Cheng, DL Motola, DJ Mangelsdorf… - Journal of Biological …, 2003 - ASBMB
The conversion of vitamin D into an active ligand for the vitamin D receptor requires 25-hydroxylation
in the liver and 1α-hydroxylation in the kidney. Mitochondrial and microsomal …

[HTML][HTML] Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase

…, JF Smith, JS Pillar, SHS Denis, JB Cheng - Journal of Biological …, 1998 - ASBMB
We have cloned and characterized the first human isozyme in a new family of cyclic nucleotide
phosphodiesterases, PDE9A. By sequence homology in the catalytic domain, PDE9A is …

[PDF][PDF] Developmental fate and cellular maturity encoded in human regulatory DNA landscapes

…, R Humbert, B Miller, SL Paige, B Vernot, JB Cheng… - Cell, 2013 - cell.com
Cellular-state information between generations of developing cells may be propagated via
regulatory regions. We report consistent patterns of gain and loss of DNase I-hypersensitive …

[HTML][HTML] Hierarchical Ti3C2Tx@ZnO Hollow Spheres with Excellent Microwave Absorption Inspired by the Visual Phenomenon of Eyeless Urchins

YQ Wang, HB Zhao, JB Cheng, BW Liu, Q Fu… - Nano-Micro Letters, 2022 - Springer
Ingenious microstructure design and rational composition selection are effective approaches
to realize high-performance microwave absorbers, and the advancement of biomimetic …

[HTML][HTML] Mammalian wax biosynthesis: I. Identification of two fatty acyl-coenzyme A reductases with different substrate specificities and tissue distributions

JB Cheng, DW Russell - Journal of biological Chemistry, 2004 - ASBMB
The conversion of fatty acids to fatty alcohols is required for the synthesis of wax monoesters
and ether lipids. The mammalian enzymes that synthesize fatty alcohols have not been …

Construction of durable eco-friendly biomass-based flame-retardant coating for cotton fabrics

AN Zhang, HB Zhao, JB Cheng, ME Li, SL Li… - Chemical Engineering …, 2021 - Elsevier
Inspired by the classic dye-fixing process, a novel eco-friendly biomass-based coating that
neither used traditional elements such as Cl, Br, P nor toxic organic solvents was first …

Isolation and characterization of PDE8A, a novel human cAMP-specific phosphodiesterase

…, JF Smith, JS Pillar, SHS Denis, JB Cheng - … and biophysical research …, 1998 - Elsevier
As part of our efforts to understand the regulation of intracellular cAMP and to generate new
targets for pharmacological intervention, we have cloned and characterized the first isozyme …

Ultralight CoNi/rGO aerogels toward excellent microwave absorption at ultrathin thickness

HB Zhao, JB Cheng, JY Zhu, YZ Wang - Journal of Materials Chemistry …, 2019 - pubs.rsc.org
Ultrathin thickness (<1 mm) and ultralow density (<10 mg cm−3) are urgent challenges for
microwave absorption materials. In this manuscript, we tackle these problems by developing a …