and the other inhibitory to rabbit’s intestine. Hirudinized blood did not yield the stimulating
substance. Hemolyzed or washed red cells gave up stimulating substance when dialyzed …

METHODS Tissues of dogs and brains of rats and rabbits were ground or homogenized with
four volumes of cold acetone and extracted below 0 C for 24-48 hours. The samples were …

1. Renin reacts with renin-activator to form a strong pressor substance which is heat-stable,
water- and alcohol-soluble, fluorescent, acid-stable, and alkali-labile. It is a reducing …

… Page (213) found that tachyphylaxis to renin developed in the isolated Page (213) found …
on plasma in vitro culminated in the extraction by Page and Helmer (224, 225) of a pressor and …

Perinephritis apparently has not been recognized as a possible cause of arterial hypertension.
Occasionally hypertension has been recorded for patients whose renal parenchyma from …

Very few substances capable, at high dilution, of effecting changes in the caliber of blood
vessels have been isolated from normal animal tissues. These are epinephrine, histamine, …

HE FACT THAT serotonin was made available in quantity shortly after its discovery has
stimulated a vast amount of fine work during the past several years. My first review in September, …

Hypertension is one of the most frequent com-plications of renaldisease, both acute and
chronic. The fact that in nephritis renal influences, nervous or other, apparently produce …

The results of these experiments indicate that the carotid and aortic baroceptor mechanisms
are reset to the hypertensive pressure levels of animals with chronic perinephritic …

… Experiments performed on dogs bv Page (48), in which renal hypertension had been
produced by constricting the renal artery (Goldblatt, Lynch, Hanzal and Summerville (49)) …