Single and double blind studies were done with single oral doses of monosodium glutamate
(MSG) in human volunteers. A total of 169 doses were given, including controls. Ninety-…

The results of these experiments indicate that many sympathomimetic amines can cause
cardiac lesions. Of the 15 compounds studied in detail, 10 caused cardiac lesions in 50% or …

The purpose of this study was to determine the mechanisms by which lesion-producing doses
of some representative sympathomimetic amines could cause impairment of myocardial …

The effects on plasma nonesterified fatty acids (NEFA) and glucose of five sympathomimetic
amines were investigated in order to determine the importance of these metabolic effects in …

Experimental bromide intoxication has been produced in dogs. Most of the classical signs of
human intoxication were reproduced. These included neurotoxicity, gastrointestinal toxicity …

SEVERAL reports (1,2) indicate that thyroid function can be distorted by therapy with I 131 .
In fact, one of the present authors reported with Dr. F. Homburger that both qualitative and …

Methods Subacute experiments in clogs 4 indicated that a daily dose of approximately 100
mg/kg. of bromide produces only minimal signs of bromide intoxication. This dose of bromide …

Tumor-bearing (glioma) mice have hepatomegaly. Although the neoplasm remains localized,
it influences hepatic triglyceride metabolism. In glioma-bearing mice, there is a quantitative …

The cardiovascular and metabolic effects of phenylephrine were investigated in dogs with
particular emphasis on correlations with myocardial oxygen (O 2 ) uptake. Phenylephrine …

Comparisons have been made between the effects of l-sparteine and oxytocin on isolated
human uterine muscles. Both drugs can initiate spontaneous contractions and this effect is …