Neutrophils play an essential role in host defense and inflammation, but the latter may trigger
and sustain the pathogenesis of a range of acute and chronic diseases. Green tea has …

Flavanols—a class of plant polyphenols abundant in tea leaves and grape seeds and skins—have
been found to inhibit some matrix-proteases instrumental in inflammation and cancer …

Hyperforin (Hyp), the major lipophilic constituent of St. John’s wort, was assayed as a stable
dicyclohexylammonium salt (Hyp-DCHA) for cytotoxicity and inhibition of matrix proteinases, …

Despite continuous improvements phosphoproteomics still faces challenges that are often
neglected, eg partially poor recovery of phosphopeptide enrichment, assessment of …

Adenosine diphosphate (ADP) enhances platelet activation by virtually any other stimulant
to complete aggregation. It binds specifically to the G-protein–coupled membrane receptors …

BACKGROUND: Some proteases involved in extracellular matrix degradation are instrumental
not only in overcoming tissue barriers to allow normal extravasation of hematic cells, but …

The postmitotic nature and longevity of skeletal muscle fibers permit stable expression of
any transfected gene. Direct in vivo injection of plasmid DNA, in both adult and regenerating …

Phosphoinositides are small phospholipids that control diverse cellular downstream signaling
events. Their spatial and temporal availability is tightly regulated by a set of specific lipid …

The anthrax lethal factor (LF) has a major role in the development of anthrax. LF is delivered
by the protective antigen (PA) inside the cell, where it exerts its metalloprotease activity on …

The advent of microfluidics has enabled thorough control of cell manipulation experiments
in so called lab on chips. Lab on chips foster the integration of actuation and detection …